Mutation
PubMed MeSh Term
Overview
subject area of
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C-elegans mitochondrial factor WAH-1 promotes phosphatidylserine externalization in apoptotic cells through phospholipid scramblase SCRM-1 Journal Article
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C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins Journal Article
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Caenorhabditis elegans drp-1 and fis-2 regulate distinct cell-death execution pathways downstream of ced-3 and independent of ced-9 Journal Article
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Drosophila Wee1 interacts with members of the γTURC and is required for proper mitotic-spindle morphogenesis and positioning Journal Article
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EIF2B2 mutations in vanishing white matter disease hypersuppress translation and delay recovery during the integrated stress response Journal Article
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In Crystallo Selection to Establish New RNA Crystal Contacts Journal Article
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Listeria monocytogenes triggers noncanonical autophagy upon phagocytosis, but avoids subsequent growth-restricting xenophagy Journal Article
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N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Reveals an Intronic Residue Critical for Caenorhabditis elegans 3 Splice Site Function in Vivo Journal Article
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Salmonella acquires ferrous iron from haemophagocytic macrophages Journal Article
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mei-41 and bub1 block mitosis at two distinct steps in response to incomplete DNA replication in Drosophila embryos Journal Article
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virK, somA and rcsC are important for systemic Salmonella enterica serovar Typhimurium infection and cationic peptide resistance Journal Article
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A CONSERVED BASE PAIR WITHIN HELIX-P4 OF THE TETRAHYMENA RIBOZYME HELPS TO FORM THE TERTIARY STRUCTURE REQUIRED FOR SELF-SPLICING Journal Article
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A CYTOGENETIC ANALYSIS OF THE PUNCH-TUDOR REGION OF CHROMOSOME-2R IN DROSOPHILA-MELANOGASTER Journal Article
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A Ras-mediated signal transduction pathway is involved in the control of sex myoblast migration in Caenorhabditis elegans Journal Article
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A bipartite polymerase-processivity factor interaction: only the internal beta binding site of the alpha subunit is required for processive replication by the DNA polymerase III holoenzyme. Journal Article
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A bulged stem tethers Est1p to telomerase RNA in budding yeast Journal Article
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A class of benzenoid chemicals suppresses apoptosis in C. elegans Journal Article
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A conditional role of U2AF in splicing of introns with unconventional polypyrimidine tracts Journal Article
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A cuticle collagen encoded by the lon-3 gene may be a target of TGF-β signaling in determining Caenorhabditis elegans body shape Journal Article
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A dominant negative mutant of the E. coli RNA helicase DbpA blocks assembly of the 50S ribosomal subunit. Journal Article
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A general method for rapid and nondenaturing purification of RNAs Journal Article
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A genetic pathway conferring life extension and resistance to UV stress in Caenorhabditis elegans Journal Article
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A genetic screen identifies novel non-compatible IoxP sites Journal Article
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A large-scale functional approach to uncover human genes and pathways in Drosophila Journal Article
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A map of constrained coding regions in the human genome Journal Article
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A metabolic model for life span determination in Caenorhabditis elegans Journal Article
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A method of mapping protein sumoylation sites by mass spectrometry using a modified small ubiquitin-like modifier 1 (SUMO-1) and a computational program Journal Article
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A mutant of Tetrahymena telomerase reverse transcriptase with increased processivity Journal Article
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A mutation associated with stress resistance in mice is associated with human grip strength and mortality Journal Article
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A mutation in the beta-myosin rod associated with hypertrophic cardiomyopathy has an unexpected molecular phenotype Journal Article
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A new fluorescence resonance energy transfer approach demonstrates that the histone variant H2AZ stabilizes the histone octamer within the nucleosome Journal Article
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A new look at the microtubule binding patterns of dimeric kinesins Journal Article
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A novel sphingolipid-TORC1 pathway critically promotes postembryonic development in Caenorhabditis elegans Journal Article
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A novel two-step genome editing strategy with CRISPR-Cas9 provides new insights into telomerase action and TERT gene expression Journal Article
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A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice Journal Article
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A systematic review and meta-analysis of 271 PCDH19-variant individuals identifies psychiatric comorbidities, and association of seizure onset and disease severity Journal Article
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A template-proximal RNA paired element contributes to Saccharomyces cerevisiae telomerase activity Journal Article
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A translation inhibitor identified in a Drosophila screen enhances the effect of ionizing radiation and taxol in mammalian models of cancer Journal Article
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A truncated cardiac troponin T molecule in transgenic mice suggests multiple cellular mechanisms for familial hypertrophic cardiomyopathy Journal Article
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A versatile and highly efficient method for scarless genome editing in Escherichia coli and Salmonella enterica Journal Article
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ACTIVATION OF THE PHOSPHOSIGNALING PROTEIN CHEY .2. ANALYSIS OF ACTIVATED MUTANTS BY F-19 NMR AND PROTEIN ENGINEERING Journal Article
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ALTERED CRO REPRESSORS FROM ENGINEERED MUTAGENESIS OF A SYNTHETIC CRO GENE Journal Article
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AMPK-FOXO-IP3R signaling pathway mediates neurological and developmental defects caused by mitochondrial DNA mutations Journal Article
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AN ULTRAVIOLET LIGHT-INDUCED CROSS-LINK IN YEAST TRANSFER RNAPHE Journal Article
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ANALYSIS INVIVO OF TRANSLATIONAL MUTANTS OF THE RIIB CISTRON OF BACTERIOPHAGE-T4 Journal Article
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ANALYSIS OF DOMINANT-NEGATIVE MUTATIONS OF THE CAENORHABDITIS-ELEGANS LET-60 RAS GENE Journal Article
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ANALYSIS OF PATTERN FORMATION IN NEUROSPORA PERITHECIAL DEVELOPMENT USING GENETIC MOSAICS Journal Article
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Absence of mutations in DICE1/DDX26 gene in human cancer cell lines with frequent 13q14 deletions Journal Article
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Accelerated protein engineering for chemical biotechnology via homologous recombination Journal Article
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Activation of DNA damage repair pathways by murine polyomavirus Journal Article
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Acute induction of conserved synaptic signaling pathways in Drosophila melanogaster. Journal Article
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Adjusting for selection on synonymous sites in estimates of evolutionary distance Journal Article
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Age-specific demographic profiles of longevity mutants in Caenorhabditis elegans show segmental effects Journal Article
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Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes Journal Article
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Allele-Specific Suppressors of lin-1(R175Opal) Identify Functions of MOC-3 and DPH-3 in tRNA Modification Complexes in Caenorhabditis elegans Journal Article
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Allele-specific differences in transcriptome, miRNome, and mitochondrial function in two hypertrophic cardiomyopathy mouse models Journal Article
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Amplicon Remodeling and Genomic Mutations Drive Population Dynamics after Segmental Amplification Journal Article
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An Essential Role of Variant Histone H3.3 for Ectomesenchyme Potential of the Cranial Neural Crest Journal Article
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An RNA internal loop acts as a hinge to facilitate ribozyme folding and catalysis Journal Article
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An early transition state for folding of the P4-P6 RNA domain Journal Article
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An integrated technology for quantitative wide mutational scanning of human antibody Fab libraries Journal Article
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An ordinary differential equation model for the multistep transformation to cancer Journal Article
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Analysis of Red-Fluorescent Proteins Provides Insight into Dark-State Conversion and Photodegradation Journal Article
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Analysis of cranial neural crest migratory pathways in axolotl using cell markers and transplantation Journal Article
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Analysis of eIF2B bodies and their relationships with stress granules and P-bodies Journal Article
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Analysis of neutral mutational drift in an allosteric enzyme Journal Article
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Analysis of telomerase catalytic subunit mutants in vivo and in vitro in Schizosaccharomyces pombe Journal Article
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Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G Journal Article
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Animal models of hypertrophic cardiomyopathy Journal Article
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Architecture of the Human and Yeast General Transcription and DNA Repair Factor TFIIH Journal Article
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Arginine methylation promotes translation repression activity of eIF4G-binding protein, Scd6 Journal Article
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Assembling a time bomb - cytochrome c oxidase and disease Journal Article
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Association of v-ErbA with Smad4 Disrupts TGF-beta Signaling Journal Article
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BACTERIAL AND PHAGE MUTATIONS THAT REVEAL HELIX-UNWINDING ACTIVITIES REQUIRED FOR BACTERIOPHAGE-T4 DNA-REPLICATION Journal Article
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BACTERIOPHAGE-T4 REGA PROTEIN - PURIFICATION OF A TRANSLATIONAL REPRESSOR Journal Article
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BASE SUBSTITUTION MUTANTS OF THE LAC OPERATOR - INVIVO AND INVITRO AFFINITIES FOR LAC REPRESSOR Journal Article
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BINDING OF THE BACTERIOPHAGE-T4 REGA PROTEIN TO MESSENGER-RNA TARGETS - AN INITIATOR AUG IS REQUIRED Journal Article
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BMP signaling patterns the dorsal and intermediate neural tube via regulation of homeobox and helix-loop-helix transcription factors Journal Article
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Bcl-2 Proteins EGL-1 and CED-9 Do Not Regulate Mitochondrial Fission or Fusion in Caenorhabditis elegans Journal Article
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Bioinformatics assessment of β-myosin mutations reveals myosin's high sensitivity to mutations Journal Article
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Biological insights from 108 schizophrenia-associated genetic loci Journal Article
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Blocking cardiac growth in hypertrophic cardiomyopathy induces cardiac dysfunction and decreased survival only in males Journal Article
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Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor Journal Article
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Bro1 coordinates deubiquitination in the multivesicular body pathway by recruiting Doa4 to endosomes. Journal Article
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Bro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae Journal Article
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Bro1 stimulates Vps4 to promote intralumenal vesicle formation during multivesicular body biogenesis Journal Article
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Budding Yeast Centrosome Duplication Requires Stabilization of Spc29 via Mps1-mediated Phosphorylation Journal Article
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C-ELEGANS LIN-45 RAF GENE PARTICIPATES IN LET-60 RAS-STIMULATED VULVAR DIFFERENTIATION Journal Article
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C2cd3 is required for cilia formation and Hedgehog signaling in mouse Journal Article
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CHEMICAL SYNTHESIS AND BIOLOGICAL STUDIES ON MUTATED GENE-CONTROL REGIONS Journal Article
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CLONING AND MOLECULAR CHARACTERIZATION OF A METABOLIC GENE WITH DEVELOPMENTAL FUNCTIONS IN DROSOPHILA .1. ANALYSIS OF THE HEAD FUNCTION OF PUNCH Journal Article
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COG-2, a Sox domain protein necessary for establishing a functional vulval-uterine connection in Caenorhabditis elegans Journal Article
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CRISPR/Cas9 recombineering-mediated deep mutational scanning of essential genes in Escherichia coli Journal Article
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CRISPR/Cas9-mediated mutagenesis in the sea lamprey Petromyzon marinus: a powerful tool for understanding ancestral gene functions in vertebrates Journal Article
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CST does not evict elongating telomerase but prevents initiation by ssDNA binding Journal Article
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Ca2+ activation of myofilaments from transgenic mouse hearts expressing R92Q mutant cardiac troponin T Journal Article
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Caenorhabditis elegans 2007: The premier model for the study of aging Journal Article
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Call activation of the cPLA(2) C2 domain: Ordered binding of two Ca2+ ions with positive cooperativity Journal Article
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Candidate exome capture identifies mutation of SDCCAG8 as the cause of a retinal-renal ciliopathy Journal Article
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Caspase-mediated activation of Caenorhabditis elegans CED-8 promotes apoptosis and phosphatidylserine externalization Journal Article
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Cdc28/Cdk1 regulates spindle pole body duplication through phosphorylation of Spc42 and Mps1 Journal Article
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Cdc42 and the actin-related protein/neural Wiskott-Aldrich syndrome protein network mediate cellular invasion by Cryptospotidium parvum Journal Article
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Cell Survival Enabled by Leakage of a Labile Metabolic Intermediate Journal Article
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Cell biology - Lessons in rational drug design for protein kinases Journal Article
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Cell corpse engulfment mediated by C-elegans phosphatidylserine receptor through CED-5 and CED-12 Journal Article
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Cells with loss-of-heterozygosity after exposure to ionizing radiation inDrosophilaare culled by p53-dependent and p53-independent mechanisms Journal Article
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Cellular Abundance of Mps1 and the Role of Its Carboxyl Terminal Tail in Substrate Recruitment Journal Article
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Characterization of the DNA-binding property of Smad5 Journal Article
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Characterizing Students' Ideas about the Effects of a Mutation in a Noncoding Region of DNA Journal Article
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Chemical inhibition of PAPD5/7 rescues telomerase function and hematopoiesis in dyskeratosis congenita Journal Article
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Chemistry of Aqueous Silica Nanoparticle Surfaces and the Mechanism of Selective Peptide Adsorption Journal Article
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Chemokine Signaling and the Regulation of Bidirectional Leukocyte Migration in Interstitial Tissues Journal Article
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Chrna4 A529 knock-in mice exhibit altered nicotine sensitivity Journal Article
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Clonal Interference, Multiple Mutations and Adaptation in Large Asexual Populations Journal Article
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Cloning and characterization of PET100, a gene required for the assembly of yeast cytochrome c oxidase Journal Article
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Cobalamin riboswitches exhibit a broad range of ability to discriminate between methylcobalamin and adenosylcobalamin Journal Article
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Codon Compression Algorithms for Saturation Mutagenesis Journal Article
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Combinatorial effect of maytansinol and radiation in Drosophila and human cancer cells Journal Article
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Common framework mutations impact antibody interfacial dynamics and flexibility Journal Article
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Comparison of crystal structure interactions and thermodynamics for stabilizing mutations in the Tetrahymena ribozyme Journal Article
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Comparison of the hammerhead cleavage reactions stimulated by monovalent and divalent cations Journal Article
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Compensatory regulation among ER chaperones in C. elegans Journal Article
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Competition between PRC2.1 and 2.2 subcomplexes regulates PRC2 chromatin occupancy in human stem cells Journal Article
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Computationally Designed Peptide Inhibitors of the Ubiquitin E3 Ligase SCFFbx4 Journal Article
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Conditional Fgfr1 Deletion in GnRH Neurons Leads to Minor Disruptions in the Reproductive Axis of Male and Female Mice Journal Article
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Conditions for mutation-order speciation Journal Article
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Conserved residues in the N-domain of the AAA+ chaperone ClpA regulate substrate recognition and unfolding Journal Article
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Constitutively active mitogen-activated protein kinase kinase 1 (MAPKK1) and MAPKK2 mediate similar transcriptional and morphological responses Journal Article
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Contractile protein mutations and heart disease Journal Article
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Contribution of rare variants to traits Journal Article
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Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation Journal Article
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Control of mitotic entry after DNA damage in Drosophila. Journal Article
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Control of sex-specific apoptosis in C-elegans by the BarH homeodomain protein CEH-30 and the transcriptional repressor UNC-37/Groucho Journal Article
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Control of somatic tissue differentiation by the long non-coding RNA TINCR Journal Article
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Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase Journal Article
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Cysteine-rich FGF receptor regulates intracellular FGF-1 and FGF-2 levels Journal Article
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Cysteine-rich fibroblast growth factor receptor alters secretion and intracellular routing of fibroblast growth factor 3 Journal Article
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DAT isn't all that: cocaine reward and reinforcement require Toll-like receptor 4 signaling Journal Article
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DELETION OF NONCONSERVED HELICES NEAR THE 3' END OF THE RIBOSOMAL-RNA INTRON OF TETRAHYMENA-THERMOPHILA ALTERS SELF-SPLICING BUT NOT CORE CATALYTIC ACTIVITY Journal Article
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DETERMINANTS OF THE 3' SPLICE SITE FOR SELF-SPLICING OF THE TETRAHYMENA PRE-RRNA Journal Article
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DETERMINATION OF THE AMOUNT OF HOMOLOGY REQUIRED FOR RECOMBINATION IN BACTERIOPHAGE-T4 Journal Article
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DIRECT IN-SITU STRUCTURAL-ANALYSIS OF RECOMBINANT OUTER-MEMBRANE PORINS EXPRESSED IN AN OMPA-DEFICIENT MUTANT ESCHERICHIA-COLI STRAIN Journal Article
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DIRECT MEASUREMENT OF OLIGONUCLEOTIDE SUBSTRATE BINDING TO WILD-TYPE AND MUTANT RIBOZYMES FROM TETRAHYMENA Journal Article
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DISRUPTION OF THE YEAST NUCLEAR PET54-GENE BLOCKS EXCISION OF MITOCHONDRIAL INTRON AL5-BETA FROM PRE-MESSENGER RNA FOR CYTOCHROME-C OXIDASE SUBUNIT-I Journal Article
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DISTRIBUTION OF TUDOR PROTEIN IN THE DROSOPHILA EMBRYO SUGGESTS SEPARATION OF FUNCTIONS BASED ON SITE OF LOCALIZATION Journal Article
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DLK-1, SEK-3 and PMK-3 Are Required for the Life Extension Induced by Mitochondrial Bioenergetic Disruption in C. elegans Journal Article
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DNA damage leads to a Cyclin A-dependent delay in metaphase-anaphase transition in the Drosophila gastrula Journal Article
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DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA. Journal Article
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DUAL TRANSLATIONAL INITIATION SITES CONTROL FUNCTION OF THE LAMBDA-S GENE Journal Article
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Decreased FGF8 signaling causes deficiency of gonadotropin-releasing hormone in humans and mice Journal Article
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Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling Journal Article
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Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis Journal Article
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Detecting Differential Transcription Factor Activity from ATAC-Seq Data Journal Article
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Detection of adamantane-resistant influenza on a microarray Journal Article
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Determinants for Efficient Editing with Cas9-Mediated Recombineering in Escherichia coli Journal Article
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Deuterium exchange mass spectrometry as a probe of protein kinase activation. Analysis of wild-type and constitutively active mutants of MAP kinase kinase-1 Journal Article
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Developmental control of convergent floral pigmentation across evolutionary timescales Journal Article
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Differential Effects of a Mutation on the Normal and Promiscuous Activities of Orthologs: Implications for Natural and Directed Evolution Journal Article
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Differential effects of Ydj1 and Sis1 on Hsp70-mediated clearance of stress granules in Saccharomyces cerevisiae Journal Article
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Direct isolation of longevity mutants in the nematode Caenorhabditis elegans Journal Article
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Directed evolution of excited state lifetime and brightness in FusionRed using a microfluidic sorter Journal Article
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Discovery of a ZIP7 inhibitor from a Notch pathway screen Journal Article
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Discrimination between Closely Related Cellular Metabolites by the SAM-I Riboswitch Journal Article
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Disease mutant analysis identifies a new function of DAXX in telomerase regulation and telomere maintenance Journal Article
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Disruption of Gpr45 causes reduced hypothalamic POMC expression and obesity Journal Article
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Dissecting Protein Function: An Efficient Protocol for Identifying Separation-of-Function Mutations That Encode Structurally Stable Proteins Journal Article
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Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage Journal Article
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Diverse chromatin remodeling genes antagonize the Rb-involved SynMuv pathways in C. elegans Journal Article
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Docking motif interactions in MAP kinases revealed by hydrogen exchange mass spectrometry Journal Article
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Drosophila ATR in double-strand break repair Journal Article
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Drosophila Polypyrimidine Tract-Binding Protein (DmPTB) Regulates Dorso-Ventral Patterning Genes in Embryos Journal Article
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Dual Host-Virus Arms Races Shape an Essential Housekeeping Protein Journal Article
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Dynamics of intrapulmonary bacterial growth in a murine model of repeated microaspiration Journal Article
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EFF-1-mediated regenerative axonal fusion requires components of the apoptotic pathway Journal Article
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EFFECT OF DNA-SEQUENCE AND STRUCTURE ON NUCLEASE ACTIVITY OF THE DEXA PROTEIN OF BACTERIOPHAGE-T4 Journal Article
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EGFRvIV: a previously uncharacterized oncogenic mutant reveals a kinase autoinhibitory mechanism Journal Article
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ELECTROFOCUSING SYSTEM FOR ANALYSIS OF PROTEINS AND THEIR GENETIC-VARIANTS Journal Article
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ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of golgi localization signals Journal Article
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ERK phosphorylation of MED14 in promoter complexes during mitogen-induced gene activation by Elk-1 Journal Article
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EXPRESSION AND FUNCTION OF CYTOCHROME-C-OXIDASE SUBUNIT ISOLOGS - MODULATORS OF CELLULAR-ENERGY PRODUCTION Journal Article
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Edc3 Function in Yeast and Mammals Is Modulated by Interaction with NAD-Related Compounds Journal Article
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Effects of Foliar Redox Status on Leaf Vascular Organization Suggest Avenues for Cooptimization of Photosynthesis and Heat Tolerance Journal Article
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Effects of Pathogenic Proline Mutations on Myosin Assembly Journal Article
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Effects of anoxia and the mitochondrion on expression of aerobic nuclear COX genes in yeast - Evidence for a signaling pathway from the mitochondrial genome to the nucleus Journal Article
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Effects of polyvalent cations on the folding of an rRNA three-way junction and binding of ribosomal protein S15 Journal Article
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Effects of transmembrane and juxtamembrane domains on proliferative ability of TSLP receptor Journal Article
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Endosomal Na+ (K+)/H+ Exchanger Nhx1/Vps44 Functions Independently and Downstream of Multivesicular Body Formation Journal Article
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Energetics and cooperativity of tertiary hydrogen bonds in RNA structure Journal Article
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Engineering cis-telomerase RNAs that add telomeric repeats to themselves Journal Article
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Enhanced product stability in the hammerhead ribozyme. Journal Article
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Ephrin signalling controls brain size by regulating apoptosis of neural progenitors Journal Article
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Epigenomic alterations define lethal CIMP-positive ependymomas of infancy Journal Article
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Equimolar addition of oligoribonucleotides with T4 RNA ligase. Journal Article
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Essential functions of amino-terminal domains in the yeast telomerase catalytic subunit revealed by selection for viable mutants Journal Article
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Estimate of the abundance of cardiomyopathic mutations in the beta-myosin gene Journal Article
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Eukaryotic Stress Granules Are Cleared by Autophagy and Cdc48/VCP Function Journal Article
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Evaluating ring-tailed lemurs (Lemur catta) from southwestern Madagascar for a genetic population bottleneck Journal Article
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Evidence that Mitotic Exit Is a Better Cancer Therapeutic Target Than Spindle Assembly Journal Article
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Evolution of Tetrahymena ribozyme mutants with increased structural stability Journal Article
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Evolution of a behavior-linked microsatellite-containing element in the 5′ flanking region of the primate AVPR1A gene Journal Article
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Evolution of vertebrate gill covers via shifts in an ancient Pou3f3 enhancer Journal Article
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Evolutionary Reconstructions of the Transferrin Receptor of Caniforms Supports Canine Parvovirus Being a Re-emerged and Not a Novel Pathogen in Dogs Journal Article
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Explaining frog deformities Journal Article
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Extending life-span in C-elegans Journal Article
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Extracellular signal-regulated kinase activates topoisomerase IIα through a mechanism independent of phosphorylation Journal Article
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FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies Journal Article
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FMRP and Ataxin-2 function together in long-term olfactory habituation and neuronal translational control Journal Article
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FUNCTIONS OF INTERMEDIATE FILAMENTS Journal Article
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Failure of translational repression in the phage f2 op3 mutant is not due to an altered coat protein-RNA interaction. Journal Article
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Fatty Acids Regulate Germline Sex Determination through ACS-4-Dependent Myristoylation Journal Article
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Fecal corticosterone levels in RCAN1 mutant mice. Journal Article
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Fibroblast growth factor deficiencies impact anxiety-like behavior and the serotonergic system Journal Article
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Filaments and phenotypes: cellular roles and orphan effects associated with mutations in cytoplasmic intermediate filament proteins. Journal Article
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Flexibility in the Periplasmic Domain of BamA Is Important for Function Journal Article
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Folic acid supplementation can adversely affect murine neural tube closure and embryonic survival Journal Article
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For the special issue: The nematode Caenorhabditis elegans in aging research Journal Article
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From sarcomeric mutations to heart disease: Understanding familial hypertrophic cardiomyopathy Journal Article
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Functional Analyses of Endometriosis-Related Polymorphisms in the Estrogen Synthesis and Metabolism-Related Genes Journal Article
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Functional Proteomics Identifies Targets of Phosphorylation by B-Raf Signaling in Melanoma Journal Article
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Functional analysis of myosin mutations that cause familial hypertrophic cardiomyopathy Journal Article
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Functional consequences of T-stem mutations in E. coli tRNAThrUGU in vitro and in vivo. Journal Article
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Functional interaction between telomere protein TPP1 and telomerase Journal Article
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Fusogenic activity of EFF-1 is regulated via dynamic localization in fusing somatic cells of C-elegans Journal Article
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G alpha 12 and G alpha 13 regulate extracellular signal-regulated kinase and c-Jun kinase pathways by different mechanisms in COS-7 cells Journal Article
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GENE OF BACTERIOPHAGE-T4 WHOSE PRODUCT PREVENTS TRUE LATE TRANSCRIPTION ON CYTOSINE-CONTAINING T4 DNA Journal Article
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GENETIC ARCHITECTURE OF OLFACTORY DISCRIMINATIVE AVOIDANCE-CONDITIONING IN DROSOPHILA-MELANOGASTER Journal Article
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GENETIC BASIS FOR A RARE FLORAL MUTANT IN AN ANDEAN SPECIES OF SOLANACEAE Journal Article
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GENETIC HITCHHIKING AND THE DYNAMIC BUILDUP OF GENOMIC DIVERGENCE DURING SPECIATION WITH GENE FLOW Journal Article
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GIANT AXONAL NEUROPATHY - A CONDITIONAL MUTATION AFFECTING CYTOSKELETAL ORGANIZATION Journal Article
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Gastrulation initiation in Caenorhabditis elegans requires the function of gad-1, which encodes a protein with WD repeats Journal Article
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Gene mutations and genomic rearrangements in the mouse as a result of transposon mobilization from chromosomal concatemers Journal Article
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Genetic Dissection of Late-Life Fertility in Caenorhabditis elegans Journal Article
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Genetic Mechanisms of Coffee Extract Protection in a Caenorhabditis elegans Model of β-Amyloid Peptide Toxicity Journal Article
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Genetic analysis of Drosophila melanogaster polytene chromosome region 44D-45F: Loci required for viability and fertility Journal Article
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Genetic analysis of ageing: Role of oxidative damage and environmental stresses Journal Article
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Genetic contribution of retinoid-related genes to neural tube defects Journal Article
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Genetic dissection of quantitative trait locus for ethanol sensitivity in long- and short-sleep mice Journal Article
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Genetic evidence that brain-derived neurotrophic factor mediates competitive interactions between individual cortical neurons Journal Article
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Genetic influences on aging Journal Article
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Genetic interactions with mutations affecting septin assembly reveal ESCRT functions in budding yeast cytokinesis Journal Article
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Genome-Wide Congealing and Rapid Transitions across the Speciation Continuum during Speciation with Gene Flow Journal Article
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Genome-Wide Expression Analysis Identifies a Modulator of Ionizing Radiation-Induced p53-Independent Apoptosis in Drosophila melanogaster Journal Article
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Genome-wide association study identifies five new schizophrenia loci Journal Article
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Genomic Deoxyxylulose Phosphate Reductoisomerase (DXR) Mutations Conferring Resistance to the Antimalarial Drug Fosmidomycin in E. coli Journal Article
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Genomic mRNA Profiling Reveals Compensatory Mechanisms for the Requirement of the Essential Splicing Factor U2AF Journal Article
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Genotype to Phenotype: A Complex Problem Journal Article
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Gerontogenes mediate health and longevity in nematodes through increasing resistance to environmental toxins and stressors Journal Article
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Glacial refugia of limber pine (Pinus flexilis James) inferred from the population structure of mitochondrial DNA Journal Article
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Glutathione activates virulence gene expression of an intracellular pathogen Journal Article
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HNRNP-L BINDS A CIS-ACTING RNA SEQUENCE ELEMENT THAT ENABLES INTRON-INDEPENDENT GENE-EXPRESSION Journal Article
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HPLC method to resolve, identify and quantify guanine nucleotides bound to recombinant ras GTPase Journal Article
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Heat shock protein accumulation is upregulated in a long-lived mutant of Caenorhabditis elegans Journal Article
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Hedgehog signalling in the mouse requires intraflagellar transport proteins Journal Article
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Hepatitis B virus X protein targets the Bcl-2 protein CED-9 to induce intracellular Ca2+ increase and cell death in Caenorhabditis elegans Journal Article
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Hidden resources in the Escherichia coli genome restore PLP synthesis and robust growth after deletion of the essential gene pdxB Journal Article
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High Throughput Sequencing Identifies Misregulated Genes in the Drosophila Polypyrimidine Tract-Binding Protein (hephaestus) Mutant Defective in Spermatogenesis Journal Article
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Histone chaperone FACT action during transcription through chromatin by RNA polymerase II Journal Article
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Homologous mutations in human β, embryonic, and perinatal muscle myosins have divergent effects on molecular power generation Journal Article
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Homozygous WNT3 mutation causes tetra-amelia in a large consanguineous family Journal Article
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Hopeful monsters and morphogens at the beach Journal Article
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Hormesis and aging in Caenorhabditis elegans Journal Article
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Hormesis in Caenorhabditis elegans dauer-defective mutants Journal Article
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Host microarray analysis reveals a role for the Salmonella response regulator phoP in human macrophage cell death Journal Article
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Hot-spot mutants of p53 core domain evince characteristic local structural changes Journal Article
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How host genetics dictates successful viral zoonosis Journal Article
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How to Recruit a Promiscuous Enzyme to Serve a New Function Journal Article
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Human ACAP2 is a homolog of C. elegans CNT-1 that promotes apoptosis in cancer cells Journal Article
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Hydrogen Bond Flexibility Correlates with Stokes Shift in mPlum Variants Journal Article
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Hydrogen deuterium exchange defines catalytically linked regions of protein flexibility in the catechol O-methyltransferase reaction Journal Article
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Hypertrophy, fibrosis, and sudden cardiac death in response to pathological stimuli in mice with mutations in cardiac troponin T Journal Article
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Hypo- and Hyper-Assembly Diseases of RNA-Protein Complexes Journal Article
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IDENTIFICATION OF AN UPSTREAM ACTIVATION SEQUENCE AND OTHER CIS-ACTING ELEMENTS REQUIRED FOR TRANSCRIPTION OF COX6 FROM SACCHAROMYCES-CEREVISIAE Journal Article
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IDENTIFICATION OF REO1, A GENE INVOLVED IN NEGATIVE REGULATION OF COX5B AND ANB1 IN AEROBICALLY GROWN SACCHAROMYCES-CEREVISIAE Journal Article
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IN-VITRO SELECTION OF SMALL RNAS THAT BIND TO ESCHERICHIA-COLI PHENYLALANYL-TRANSFER-RNA SYNTHETASE Journal Article
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INCREASED LIFE-SPAN OF AGE-1 MUTANTS IN CAENORHABDITIS-ELEGANS AND LOWER GOMPERTZ RATE OF AGING Journal Article
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INHIBITION OF RNA CLEAVAGE BUT NOT POLYADENYLATION BY A POINT MUTATION IN MESSENGER RNA-3' CONSENSUS SEQUENCE AAUAAA Journal Article
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ISOLATION AND CHARACTERIZATION OF A NEMATODE TRANSPOSABLE ELEMENT FROM PANAGRELLUS-REDIVIVUS Journal Article
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ISOLATION AND CHARACTERIZATION OF A YEAST-STRAIN CARRYING A MUTATION IN THE MITOCHONDRIAL PROMOTER FOR COX2 Journal Article
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Identification and analysis of the interaction between Edc3 and Dcp2 in Saccharomyces cerevisiae. Journal Article
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Identification of human TERT elements necessary for telomerase recruitment to telomeres Journal Article
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Identification of novel MAP kinase pathway signaling targets by functional proteomics and mass spectrometry Journal Article
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Identification of the acidic residues in the active site of DNA polymerase III. Journal Article
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Identification of thermodynamically relevant interactions between EF-Tu and backbone elements of tRNA Journal Article
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Identifying Recent Adaptations in Large-Scale Genomic Data Journal Article
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Identifying domains of EFHC1 involved in ciliary localization, ciliogenesis, and the regulation of Wnt signaling Journal Article
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Idiosyncratic tuning of tRNAs to achieve uniform ribosome binding. Journal Article
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Impact of In Vivo Protein Folding Probability on Local Fitness Landscapes Journal Article
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In vitro selection of the Naegleria GIR1 ribozyme identifies three base changes that dramatically improve activity Journal Article
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In vivo selection of better self-splicing introns in Escherichia coli:: The role of the P1 extension helix of the Tetrahymena intron Journal Article
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Increasing our ability to predict contemporary evolution Journal Article
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Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo Journal Article
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Induction of mitogen-activated protein kinase phosphatase 1 by the stress-activated protein kinase signaling pathway but not by extracellular signal-regulated kinase in fibroblasts Journal Article
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Inhibiting the TLR4-MyD88 signalling cascade by genetic or pharmacological strategies reduces acute alcohol-induced sedation and motor impairment in mice Journal Article
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Inhibition of CED-3 zymogen activation and apoptosis in Caenorhabditis elegans by caspase homolog CSP-3 Journal Article
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Inhibition of Telomerase Recruitment and Cancer Cell Death Journal Article
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Inhibitors of PARP: Number crunching and structure gazing Journal Article
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Insights into Human β-Cardiac Myosin Function from Single Molecule and Single Cell Studies Journal Article
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Insights into cellulase-lignin non-specific binding revealed by computational redesign of the surface of green fluorescent protein Journal Article
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Intermittent treatment of BRAFV600E melanoma cells delays resistance by adaptive resensitization to drug rechallenge Journal Article
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Interplay between AAUAAA and the trans-splice site in processing of a Caenorhabditis elegans operon pre-mRNA. Journal Article
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Investigating the mutation resistance of nonnucleoside inhibitors of HIV-RT using multiple microsecond atomistic simulations Journal Article
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Isolated Bacterial Chemosensory Array Possesses Quasi- and Ultrastable Components: Functional Links between Array Stability, Cooperativity, and Order Journal Article
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Isolation and characterization of two mutant forms of T4 polynucleotide kinase. Journal Article
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Isolation of Intrinsically Active (MEK-independent) Variants of the ERK Family of Mitogen-activated Protein (MAP) Kinases Journal Article
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Isolation of long-lived mutants in Caenorhabditis elegans using selection for resistance to juglone Journal Article
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James V. Neel and Yuri E. Dubrova: Cold War Debates and the Genetic Effects of Low-Dose Radiation Journal Article
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LAC UP-PROMOTER MUTANTS WITH INCREASED HOMOLOGY TO THE CONSENSUS PROMOTER SEQUENCE Journal Article
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LEAD-CATALYZED CLEAVAGE OF YEAST TRANSFER RNAPHE MUTANTS Journal Article
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LINC00520 is induced by Src, STAT3, and PI3K and plays a functional role in breast cancer Journal Article
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Labeled EF-Tus for rapid kinetic studies of pretranslocation complex formation. Journal Article
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Leveraging dominant-negative histone H3 K-to-M mutations to study chromatin during differentiation and development Journal Article
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Limb mutants: what can they tell us about normal limb development? Journal Article
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Lin-35/Rb cooperates with the SWI/SNF complex to control Caenorhabditis elegans larval development Journal Article
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Long-lived mitochondrial (Mit) mutants of Caenorhabditis elegans utilize a novel metabolism Journal Article
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Longevity genes in the nematode Caenorhabditis elegans also mediate increased resistance to stress and prevent disease Journal Article
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MECHANISM OF DNA-REPLICATION FIDELITY FOR 3 MUTANTS OF DNA-POLYMERASE-I - KLENOW FRAGMENT KF(EXO+), KF(POLA5), AND KF(EXO-) Journal Article
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MITOCHONDRIAL GENE-EXPRESSION IN SACCHAROMYCES-CEREVISIAE .2. FIDELITY OF TRANSLATION IN ISOLATED-MITOCHONDRIA FROM WILD-TYPE AND RESPIRATORY-DEFICIENT MUTANT-CELLS Journal Article
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MITOCHONDRIAL-FUNCTION IN NORMAL AND GENETICALLY ALTERED CELLS AND TISSUES Journal Article
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MOLECULAR ANALYSIS OF NO-ON-TRANSIENT-A, A GENE REQUIRED FOR NORMAL VISION IN DROSOPHILA Journal Article
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MOLECULAR GENETIC-STUDIES OF THE CDC7 PROTEIN-KINASE AND INDUCED MUTAGENESIS IN YEAST Journal Article
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MOVEMENT AS AN INDEX OF VITALITY - COMPARING WILD-TYPE AND THE AGE-1 MUTANT OF CAENORHABDITIS-ELEGANS Journal Article
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MUTANT EXPRESSION OF MALE COPULATORY BURSA SURFACE-MARKERS IN CAENORHABDITIS-ELEGANS Journal Article
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MUTANTS OF THE BACTERIOPHAGE-MS2 COAT PROTEIN THAT ALTER ITS COOPERATIVE BINDING TO RNA Journal Article
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MUTANTS OF THE LAC PROMOTER WITH LARGE INSERTIONS AND DELETIONS BETWEEN THE CAP BINDING-SITE AND THE -35 REGION Journal Article
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MUTATION THAT CONFERS TEMPERATURE SENSITIVITY ON TRANSLATION OF RIIB IN BACTERIOPHAGE-T4 Journal Article
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MUTATIONS AFFECTING TRANSLATION OF THE BACTERIOPHAGE-T4 RIIB GENE CLONED IN ESCHERICHIA-COLI Journal Article
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MUTATIONS THAT DETOXIFY AN ABERRANT T4 MEMBRANE-PROTEIN Journal Article
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Many disease-associated variants of hTERT retain high telomerase enzymatic activity Journal Article
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Maximum likelihood estimation of ancestral codon usage bias parameters in Drosophila. Journal Article
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Mcm10 and Cdc45 cooperate in origin activation in Saccharomyces cerevisiae Journal Article
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Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins Journal Article
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Measurement of respiration rates of Methylobacterium extorquens AM1 cultures by use of a phosphorescence-based sensor. Journal Article
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Mechanics of Hsp70 chaperones enables differential interaction with client proteins Journal Article
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Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans Journal Article
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Mechanisms of Disease: insights into X-linked and autosomal-dominant Kallmann syndrome Journal Article
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Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire Journal Article
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Mechanisms of the pathogenesis of troponin T-based familial hypertrophic cardiomyopathy Journal Article
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Mediator and post-recruitment regulation of RNA polymerase II. Journal Article
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Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase Journal Article
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Mesenchymal and MAPK Expression Signatures Associate with Telomerase Promoter Mutations in Multiple Cancers Journal Article
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Mice expressing mutant myosin heavy chains are a model for familial hypertrophic cardiomyopathy Journal Article
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Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size Journal Article
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Minimal and extended hammerheads utilize a similar dynamic reaction mechanism for catalysis. Journal Article
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Mitochondrial Dysfunction in C. elegans Activates Mitochondrial Relocalization and Nuclear Hormone Receptor-Dependent Detoxification Genes Journal Article
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Mitochondrial protein oxidation in yeast mutants lacking manganese- (MnSOD) or copper- and zinc-containing superoxide dismutase (CuZnSOD) - Evidence that MnSOD and CuZnSOD have both unique and overlapping functions in protecting mitochondrial proteins from oxidative damage Journal Article
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Mitotic phosphorylation of Golgi reassembly stacking protein 55 by mitogen-activated protein kinase ERK2 Journal Article
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Modifiers of notch transcriptional activity identified by genome-wide RNAi Journal Article
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Modifying the specificity of an RNA backbone contact Journal Article
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Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR-1 kinase and PP2A phosphatase Journal Article
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Modulation of ionizing radiation-induced apoptosis by bantam microRNA in Drosophila Journal Article
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Modulation of tRNAAla identity by inorganic pyrophosphatase Journal Article
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Molecular Mechanism of an Oncogenic Mutation That Alters Membrane Targeting: Glu17Lys Modifies the PIP Lipid Specificity of the AKT1 PH Domain Journal Article
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Molecular and biochemical characterization of the Skp2-Cks1 binding interface Journal Article
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Molecular evolution of anthocyanin pigmentation genes following losses of flower color Journal Article
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Molecular functions of the TLE tetramerization domain in Wnt target gene repression Journal Article
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Molecular genetic mechanisms of life span manipulation in Caenorhabditis elegans Journal Article
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Molecular genetics of macular dystrophies Journal Article
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Molecular interactions and metal binding in the theophylline-binding core of an RNA aptamer Journal Article
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Molecular tuning of an EF-hand-like calcium binding loop - Contributions of the coordinating side chain at loop position 3 Journal Article
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Multiple cancers escape from multiple MAPK pathway inhibitors and use DNA replication stress signaling to tolerate aberrant cell cycles Journal Article
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Multiple mechanisms are involved in regulating the expression of the developmental timing regulator lin-28 in Caenorhabditis elegans Journal Article
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Multiplex navigation of global regulatory networks (MINR) in yeast for improved ethanol tolerance and production Journal Article
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Multiplexed tracking of combinatorial genomic mutations in engineered cell populations Journal Article
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Mutagenesis and comparative sequence analysis of a base triple joining the two domains of group I ribozymes Journal Article
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Mutation Carriers with Reduced C-Afferent Density Reveal Cortical Dynamics of Pain-Action Relationship during Acute Pain Journal Article
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Mutation in TERT separates processivity from anchor-site function Journal Article
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Mutation of the TERT promoter, switch to active chromatin, and monoallelic TERT expression in multiple cancers Journal Article
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Mutation of the IIB myosin heavy chain gene results in muscle fiber loss and compensatory hypertrophy Journal Article
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Mutation of the?5 nicotinic acetylcholine receptor subunit increases ethanol and nicotine consumption in adolescence and impacts adult drug consumption Journal Article
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Mutation-order divergence by sexual selection: diversification of sexual signals in similar environments as a first step in speciation Journal Article
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Mutational analysis of the purine riboswitch aptamer domain Journal Article
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Mutations at the same amino acid in myosin that cause either skeletal or cardiac myopathy have distinct molecular phenotypes Journal Article
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Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 Are Identified in Individuals with Congenital Hypogonadotropic Hypogonadism Journal Article
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Mutations in KIF7 implicated in idiopathic scoliosis in humans and axial curvatures in zebrafish Journal Article
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Mutations in a newly identified Drosophila melanogaster gene, mago nashi, disrupt germ cell formation and result in the formation of mirror-image symmetrical double abdomen embryos. Journal Article
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Mutations in cye-1, a Caenorhabditis elegans cyclin E homolog, reveal coordination between cell-cycle control and vulval development Journal Article
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Mutations in the Tetrahymena ribozyme internal guide sequence: Effects on docking of the P1 helix into the catalytic core and correlation with catalytic activity Journal Article
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Mutations in the β-myosin rod cause myosin storage myopathy via multiple mechanisms Journal Article
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Mutations that improve efficiency of a weak-link enzyme are rare compared to adaptive mutations elsewhere in the genome Journal Article
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Myocyte enhancer factor-2 and serum response factor binding elements regulate fast myosin heavy chain transcription in vivo Journal Article
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NFATc2 recruits cJun homodimers to an NFAT site to synergistically activate interleukin-2 transcription Journal Article
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NUCLEAR FUNCTIONS REQUIRED FOR CYTOCHROME-C-OXIDASE BIOGENESIS IN SACCHAROMYCES-CEREVISIAE - CHARACTERIZATION OF MUTANTS IN 34 COMPLEMENTATION GROUPS Journal Article
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NUCLEAR GENES FOR MITOCHONDRIAL PROTEINS - IDENTIFICATION AND ISOLATION OF A STRUCTURAL GENE FOR SUBUNIT-V OF YEAST CYTOCHROME-C OXIDASE Journal Article
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NUCLEOTIDES IN YEAST TRANSFER RNAPHE REQUIRED FOR THE SPECIFIC RECOGNITION BY ITS COGNATE SYNTHETASE Journal Article
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NUMBERING SYSTEM FOR THE HAMMERHEAD Journal Article
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Natural and artificial RNAs occupy the same restricted region of sequence space Journal Article
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Neuronal Regulation of eIF2α Function in Health and Neurological Disorders Journal Article
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Nonadaptive explanations for signatures of partial selective sweeps in Drosophila Journal Article
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Notch mRNA Expression in Drosophila Embryos Is Negatively Regulated at the Level of mRNA 3 ' Processing Journal Article
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Novel FGF8 Mutations Associated with Recessive Holoprosencephaly, Craniofacial Defects, and Hypothalamo-Pituitary Dysfunction Journal Article
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Novel function of the flap endonuclease 1 complex in processing stalled DNA replication forks Journal Article
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Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains Journal Article
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Nucleosome-binding affinity as a primary determinant of the nuclear mobility of the pioneer transcription factor FoxA Journal Article
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Nucleotide levels regulate germline proliferation through modulating GLP-1/Notch signaling in C. elegans Journal Article
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Number of Nevi and early-life ambient UV exposure are associated with BRAF-mutant melanoma Journal Article
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OLIGONUCLEOTIDE MUTAGENESIS OF THE LACPUV5 PROMOTER Journal Article
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ON THE ROLE OF THE SINGLE-STRANDED-DNA BINDING-PROTEIN OF BACTERIOPHAGE-T4 IN DNA METABOLISM .1. ISOLATION AND GENETIC-CHARACTERIZATION OF NEW MUTATIONS IN GENE-32 OF BACTERIOPHAGE-T4 Journal Article
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ONE BINDING-SITE DETERMINES SEQUENCE SPECIFICITY OF TETRAHYMENA PRE-RIBOSOMAL-RNA SELF-SPLICING, TRANSSPLICING, AND RNA ENZYME-ACTIVITY Journal Article
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OPTIMAL CHEMOSTAT CASCADES FOR PERIPLASMIC PROTEIN-PRODUCTION Journal Article
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OVEREXPRESSION OF A LEADERLESS FORM OF YEAST CYTOCHROME-C-OXIDASE SUBUNIT-VA CIRCUMVENTS THE REQUIREMENT FOR A LEADER PEPTIDE IN MITOCHONDRIAL IMPORT Journal Article
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Oncogenic B-Raf signaling in melanoma cells controls a network of microRNAs with combinatorial functions Journal Article
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Oncogenic mutant forms of EGFR: Lessons in signal transduction and targets for cancer therapy Journal Article
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Optimization of multi-site nicking mutagenesis for generation of large, user-defined combinatorial libraries Journal Article
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Owl monkey CCR5 reveals synergism between CD4 and CCR5 in HIV-1 entry Journal Article
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Oxygen sensing in yeast: Evidence for the involvement of the respiratory chain in regulating the transcription of a subset of hypoxic genes Journal Article
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P-Type ATPase TAT-2 Negatively Regulates Monomethyl Branched-Chain Fatty Acid Mediated Function in Post-Embryonic Growth and Development in C. elegans Journal Article
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PARN Modulates Y RNA Stability and Its 3′-End Formation Journal Article
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PARTIAL CDNA SEQUENCE TO A HAMSTER GENE CORRECTS DEFECT IN ESCHERICHIA-COLI PYRB MUTANT Journal Article
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PI(3,5)P-2 controls vacuole potassium transport to support cellular osmoregulation Journal Article
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POINT MUTATIONS OF THE ADENOVIRUS MAJOR LATE PROMOTER WITH DIFFERENT TRANSCRIPTIONAL EFFICIENCIES INVITRO Journal Article
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POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates Journal Article
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PRODUCTION OF AGE-SYNCHRONOUS MASS-CULTURES OF CAENORHABDITIS-ELEGANS Journal Article
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Parsing age, mutations and time Journal Article
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Pathway- and expression level-dependent effects of oncogenic N-Ras:: p27Kip1 mislocalization by the Ral-GEF pathway and Erk-mediated interference with Smad signaling Journal Article
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Patterns of mutation and selection at synonymous sites in Drosophila. Journal Article
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Pharmacologic inhibitors of MKK1 and MKK2 Journal Article
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Phenotypic analysis of separation-of-function alleles of MEI-41, Drosophila ATM/ATR Journal Article
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Phosphorylation of Human Papillomavirus Type 16 L2 Contributes to Efficient Virus Infectious Entry Journal Article
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Phosphorylation regulates human OCT4 Journal Article
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Polymerization, three-dimensional structure and mechanical properties of Dictyostelium versus rabbit muscle actin filaments Journal Article
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Polynucleotide kinase from a T4 mutant which lacks the 3' phosphatase activity. Journal Article
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Posttranscriptional modulation of TERC by PAPD5 inhibition rescues hematopoietic development in dyskeratosis congenita Journal Article
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Potassium dependent rescue of a myopathy with core-like structures in mouse Journal Article
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Predicting Drug Resistance Using Deep Mutational Scanning Journal Article
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Predicting longevity in C-elegans: Fertility, mobility and gene expression Journal Article
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Progression from hypertrophic to dilated cardiomyopathy in mice that express a mutant myosin transgene Journal Article
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Promotion of vesicular zinc efflux by ZIP13 and its implications for spondylocheiro dysplastic Ehlers-Danlos syndrome Journal Article
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Proteasome Activation is Mediated via a Functional Switch of the Rpt6 C-terminal Tail Following Chaperone-dependent Assembly Journal Article
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QUANTITATIVE-ANALYSIS OF THE RELATIONSHIP BETWEEN NUCLEOTIDE-SEQUENCE AND FUNCTIONAL-ACTIVITY Journal Article
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Qualifying for the license to replicate. Journal Article
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Quality control of assembly-defective U1 snRNAs by decapping and 5′-to-3′ exonucleolytic digestion Journal Article
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Quantification of Inbreeding Due to Distant Ancestors and Its Detection Using Dense Single Nucleotide Polymorphism Data Journal Article
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Quantitative proteomics identifies proteins that resist translational repression and become dysregulated in ALS-FUS Journal Article
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RAPID METHOD FOR ISOLATION AND SCREENING OF CYTOCHROME-C OXIDASE-DEFICIENT MUTANTS OF SACCHAROMYCES-CEREVISIAE Journal Article
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RAS FARNESYLTRANSFERASE INHIBITORS SUPPRESS THE PHENOTYPE RESULTING FROM AN ACTIVATED RAS MUTATION IN CAENORHABDITIS-ELEGANS Journal Article
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RECOGNITION OF TERTIARY STRUCTURE IN TRANSFER-RNAS BY RH(PHEN)2PHI3+, A NEW REAGENT FOR RNA STRUCTURE-FUNCTION MAPPING Journal Article
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REGULATION OF GENE-32 EXPRESSION DURING BACTERIOPHAGE-T4 INFECTION OF ESCHERICHIA-COLI Journal Article
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REO1 and ROX1 are alleles of the same gene which encodes a transcriptional repressor of hypoxic genes in Saccharomyces cerevisiae Journal Article
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RESCUE OF THE DROSOPHILA PHOTOTRANSDUCTION MUTATION TRP BY GERMLINE TRANSFORMATION Journal Article
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RESOLVING THE FUNCTIONS OF OVERLAPPING VIRAL GENES BY SITE-SPECIFIC MUTAGENESIS AT A MESSENGER-RNA SPLICE SITE Journal Article
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RNA aptamers as pathway-specific MAP kinase inhibitors Journal Article
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RNA recognition by the DNA end-binding Ku heterodimer Journal Article
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ROLE OF CONSERVED SEQUENCE ELEMENT-9L AND ELEMENT-2 IN SELF-SPLICING OF THE TETRAHYMENA RIBOSOMAL-RNA PRECURSOR Journal Article
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ROLE OF THE CRO REPRESSOR CARBOXY-TERMINAL DOMAIN AND FLEXIBLE DIMER LINKAGE IN OPERATOR AND NONSPECIFIC DNA-BINDING Journal Article
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ROLE OF THE TERTIARY NUCLEOTIDES IN THE INTERACTION OF YEAST PHENYLALANINE TRANSFER-RNA WITH ITS COGNATE SYNTHETASE Journal Article
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Rab10 GTPase regulates ER dynamics and morphology. Journal Article
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Rapid evolution of BRCA1 and BRCA2 in humans and other primates Journal Article
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Rapid speciation via the evolution of pre-mating isolation in the Ibera Seedeater Journal Article
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Rasal2 deficiency reduces adipogenesis and occurrence of obesity-related disorders Journal Article
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Reconciliation of daf-2 suppression by elt-3 in Caenorhabditis elegans from Tonsaker et al. (2012) and Kim et al. (2012) Journal Article
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Reduced expression of the Caenorhabditis elegans p53 ortholog cep-1 results in increased longevity Journal Article
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Regulated interactions between dynamin and the actin-binding protein cortactin modulate cell shape Journal Article
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Regulation of mitosis in response to damaged or incompletely replicated DNA require different levels of Grapes (Drosophila Chk1) Journal Article
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Regulation of myostatin expression and myoblast differentiation by FoxO and SMAD transcription factors Journal Article
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Regulatory approved monoclonal antibodies contain framework mutations predicted from human antibody repertoires Journal Article
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Relationship between Candida albicans virulence during experimental hematogenously disseminated infection and endothelial cell damage in vitro. Journal Article
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Relationship between increased longevity and stress resistance as assessed through gerontogene mutations in Caenorhabditis elegans Journal Article
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Repetitive element transcripts are elevated in the brain of C9orf72 ALS/FTLD patients Journal Article
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Repression of Germline RNAi Pathways in Somatic Cells by Retinoblastoma Pathway Chromatin Complexes Journal Article
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Retroviruses facilitate the rapid evolution of the mammalian placenta Journal Article
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Role of ANC-1 in tethering nuclei to the actin cytoskeleton. Journal Article
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Role of C-elegans lin-40 MTA in vulval fate specification and morphogenesis Journal Article
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Role of light and jasmonic acid signaling in regulating foliar phloem cell wall ingrowth development Journal Article
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SELECTION AND CHARACTERIZATION OF RNAS REPLICATED BY Q-BETA REPLICASE Journal Article
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SEQUENCE REQUIREMENTS FOR SELF-SPLICING OF THE TETRAHYMENA-THERMOPHILA PRE-RIBOSOMAL RNA Journal Article
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SEQUENCES AND STUDIES OF BACTERIOPHAGE-T4 RII-MUTANTS Journal Article
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SNARE bundle and syntaxin N-peptide constitute a minimal complement for Munc18-1 activation of membrane fusion Journal Article
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STRUCTURES INVOLVED IN TETRAHYMENA RIBOSOMAL-RNA SELF-SPLICING AND RNA ENZYME-ACTIVITY Journal Article
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STUDIES ON GENE CONTROL REGIONS .3. BINDING OF SYNTHETIC AND MODIFIED SYNTHETIC LAC OPERATOR DNAS TO LACTOSE REPRESSOR Journal Article
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STUDIES ON GENE-CONTROL REGIONS .10. EFFECT OF SPECIFIC ADENINE-THYMINE TRANSVERSIONS ON THE LAC REPRESSOR-LAC OPERATOR INTERACTION Journal Article
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STUDIES ON GENE-CONTROL REGIONS .12. FUNCTIONAL-SIGNIFICANCE OF A LAC OPERATOR CONSTITUTIVE MUTATION Journal Article
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SUMO-1 modification of MEF2A regulates its transcriptional activity Journal Article
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SUR-2, A NOVEL GENE, FUNCTIONS LATE IN THE LET-60 RAS-MEDIATED SIGNALING PATHWAY DURING CAENORHABDITIS-ELEGANS VULVAR INDUCTION Journal Article
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SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C-elegans Journal Article
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SYNTHESIS AND BIOLOGICAL-ACTIVITY OF A LAMBDA-PSEUDO OPERATOR Journal Article
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Saturation Mutagenesis Genome Engineering of Infective Phi X174 Bacteriophage via Unamplified Oligo Pools and Golden Gate Assembly Journal Article
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Schizosaccharomyces pombe mst2(+) encodes a MYST family histone acetyltransferase that negatively regulates telomere silencing Journal Article
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Screening for Radiation Sensitizers of Drosophila Checkpoint Mutants Journal Article
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Sedimentation Velocity Analysis with Fluorescence Detection of Mutant Huntingtin Exon 1 Aggregation in Drosophila melanogaster and Caenorhabditis elegans Journal Article
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Selective activation of cognate SNAREpins by Sec1/Munc18 proteins Journal Article
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Sequestration of a highly reactive intermediate in an evolving pathway for degradation of pentachlorophenol Journal Article
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Serine residues in the α4 nicotinic acetylcholine receptor subunit regulate surface α4β2☆ receptor expression and clustering Journal Article
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Shared genetic architecture across psychiatric disorders Journal Article
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Signaling and sensory adaptation in Escherichia coli chemoreceptors: 2015 update Journal Article
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Single-stranded telomere-binding protein employs a dual rheostat for binding affinity and specificity that drives function Journal Article
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Smaller inner ear sensory epithelia in Neurog1 null mice are related to earlier hair cell cycle exit Journal Article
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Soluble domains of telomerase reverse transcriptase identified by high-throughput screening Journal Article
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Somatic sex determination in Caenorhabditis elegans is modulated by SUP-26 repression of tra-2 translation Journal Article
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Soy diet worsens heart disease in mice Journal Article
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Spatial shaping of cochlear innervation by temporally regulated neurotrophin expression Journal Article
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Specific translocation of protein kinase Cα to the plasma membrane requires both Ca2+ and PIP2 recognition by its C2 domain Journal Article
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Stabilization of the SARS-CoV-2 receptor binding domain by protein core redesign and deep mutational scanning Journal Article
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Stable binding of ATF6 to BiP in the endoplasmic reticulum stress response Journal Article
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Stable isotopic signature of dissimilatory nitrate reduction is robust against enzyme mutation Journal Article
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Structural Basis for Substrate Specificity in ArnB. A Key Enzyme in the Polymyxin Resistance Pathway of Gram-Negative Bacteria Journal Article
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Structural Basis of Selective Ubiquitination of TRF1 by SCFFbx4 Journal Article
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Structural and functional analyses of hepatitis B virus X protein BH3-like domain and Bcl-xL interaction Journal Article
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Structural and mechanistic insights into Mps1 kinase activation Journal Article
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Structural basis for diversity in the SAM clan of riboswitches Journal Article
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Structural basis for recognition of S-adenosylhomocysteine by riboswitches Journal Article
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Structural basis of the enhanced stability of a mutant ribozyme domain and a detailed view of RNA-solvent interactions Journal Article
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Structural distortion of p53 by the mutation R249S and its rescue by a designed peptide:: Implications for "Mutant conformation" Journal Article
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Structural mechanism of mitochondrial membrane remodelling by human OPA1 Journal Article
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Structural, biochemical, and functional analyses of CED-9 recognition by the proapoptotic proteins EGL-1 and CED-4 Journal Article
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Structure and dynamic behavior of nucleosomes Journal Article
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Structure and function analysis of the C-elegans aminophospholipid translocase TAT-1 Journal Article
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Structure and mechanism of ArnA: Conformational change implies ordered dehydrogenase mechanism in key enzyme for polymyxin resistance Journal Article
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Structure of Mediator of RhoA-Dependent Invasion (MRDI) Explains Its Dual Function as a Metabolic Enzyme and a Mediator of Cell Invasion Journal Article
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Structure of the forkhead domain of FOXP2 bound to DNA Journal Article
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Structure-guided Mutational Analysis of Gene Regulation by the Bacillus subtilis pbuE Adenine-responsive Riboswitch in a Cellular Context Journal Article
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Structures of Merkel Cell Polyomavirus VP1 Complexes Define a Sialic Acid Binding Site Required for Infection Journal Article
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Suppression of nonsense mutations in cell culture and mice by multimerized suppressor tRNA genes Journal Article
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Surfing downhill: when should population range expansion be characterized by reductions in fitness? Journal Article
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SynMuv genes redundantly inhibit lin-31EGF expression to prevent inappropriate vulval induction in C-elegans Journal Article
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Syntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE-Sec1/Munc18 membrane fusion complex Journal Article
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Synthetic chimeric nucleases function for efficient genome editing Journal Article
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Systematic evaluation of C-elegans lincRNAs with CRISPR knockout mutants Journal Article
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Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2 Journal Article
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TARGETED DISRUPTION OF THE BDNF GENE PERTURBS BRAIN AND SENSORY NEURON DEVELOPMENT BUT NOT MOTOR-NEURON DEVELOPMENT Journal Article
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TFIIA changes the conformation of the DNA in TBP/TATA complexes and increases their kinetic stability Journal Article
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THE ALBINO-DELETION COMPLEX IN THE MOUSE DEFINES GENES NECESSARY FOR DEVELOPMENT OF EMBRYONIC AND EXTRAEMBRYONIC ECTODERM Journal Article
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THE BACTERIOPHAGE-T4 DEXA-GENE - SEQUENCE AND ANALYSIS OF A GENE CONDITIONALLY REQUIRED FOR DNA-REPLICATION Journal Article
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THE C-ELEGANS KSR-1 GENE ENCODES A NOVEL RAF-RELATED KINASE INVOLVED IN RAS-MEDIATED SIGNAL-TRANSDUCTION Journal Article
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THE CONSERVED U.G PAIR IN THE 5' SPLICE SITE DUPLEX OF A GROUP-I INTRON IS REQUIRED IN THE 1ST BUT NOT THE 2ND STEP OF SELF-SPLICING Journal Article
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THE DISSONANCE MUTATION AT THE NO-ON-TRANSIENT-A LOCUS OF DROSOPHILA-MELANOGASTER - GENETIC-CONTROL OF COURTSHIP SONG AND VISUAL BEHAVIORS BY A PROTEIN WITH PUTATIVE RNA-BINDING MOTIFS Journal Article
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THE DISTRIBUTION OF CYTOPLASMIC ACTIN IN MOUSE 8-CELL BLASTOMERES Journal Article
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THE REX SYSTEM OF BACTERIOPHAGE-LAMBDA - TOLERANCE AND ALTRUISTIC CELL-DEATH Journal Article
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THE TETRAHYMENA RIBOZYME ACTS LIKE AN RNA RESTRICTION ENDONUCLEASE Journal Article
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THERMOTOLERANCE AND EXTENDED LIFE-SPAN CONFERRED BY SINGLE-GENE MUTATIONS AND INDUCED BY THERMAL-STRESS Journal Article
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THERMOTOLERANCE OF A LONG-LIVED MUTANT OF CAENORHABDITIS-ELEGANS Journal Article
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TRANSFORMATION OF MAMMALIAN-CELLS BY CONSTITUTIVELY ACTIVE MAP KINASE KINASE Journal Article
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TRANSLATIONAL INITIATION IN PROKARYOTES Journal Article
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TRANSLATIONAL REINITIATION IN THE RIIB CISTRON OF BACTERIOPHAGE-T4 Journal Article
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TRIM28 is a transcriptional activator of the mutant TERT in human bladder cancer Journal Article
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TUDOR, A POSTERIOR-GROUP GENE OF DROSOPHILA-MELANOGASTER, ENCODES A NOVEL PROTEIN AND AN MESSENGER-RNA LOCALIZED DURING MID-OOGENESIS Journal Article
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Targeted CRISPR disruption reveals a role for RNase MRP RNA in human preribosomal RNA processing Journal Article
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Targeting the sarcomere in inherited cardiomyopathies Journal Article
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Telomerase in Bladder Cancer: Back to a Better Future? Journal Article
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Telomere Replication Stress Induced by POT1 Inactivation Accelerates Tumorigenesis Journal Article
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Telomere biology disorders: time for moving towards the clinic? Journal Article
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Tetrahymena Telomerase Protein p65 Induces Conformational Changes throughout Telomerase RNA (TER) and Rescues Telomerase Reverse Transcriptase and TER Assembly Mutants Journal Article
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The C-elegans evl-20 gene is a homolog of the small GTPase ARL2 and regulates cytoskeleton dynamics during cytokinesis and morphogenesis Journal Article
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The Caenorhabditis elegans aristaless orthologue, alr-1, is required for maintaining the functional and structural integrity of the amphid sensory organs Journal Article
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The Caenorhabditis elegans nuclear receptor gene nhr-25 regulates epidermal cell development Journal Article
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The Hectd1 ubiquitin ligase is required for development of the head mesenchyme and neural tube closure Journal Article
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The trans-SNARE-regulating function of Munc18-1 is essential to synaptic exocytosis Journal Article
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The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer Journal Article
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The Continuing Challenge of Understanding, Preventing, and Treating Neural Tube Defects Journal Article
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The GATA Factor elt-1 Regulates C. elegans Developmental Timing by Promoting Expression of the let-7 Family MicroRNAs Journal Article
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The Hypertrophic Cardiomyopathy Myosin Mutation R453C Alters ATP Binding and Hydrolysis of Human Cardiac β- Myosin* Journal Article
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The Influence of Polyploidy on the Evolution of Yeast Grown in a Sub-Optimal Carbon Source Journal Article
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The KASH domain protein MSP-300 plays an essential role in nuclear anchoring during Drosophila oogenesis Journal Article
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The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis Journal Article
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The Rcs phosphorelay system is specific to enteric pathogens/commensals and activates ydeI, a gene important for persistent Salmonella infection of mice Journal Article
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The Resistome: A Comprehensive Database of Escherichia coli Resistance Phenotypes Journal Article
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The Structure of a BamA-BamD Fusion Illuminates the Architecture of the β-Barrel Assembly Machine Core Journal Article
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The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity Journal Article
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The Vitamin K Epoxide Reductase Vkorc1l1 Promotes Preadipocyte Differentiation in Mice Journal Article
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The anticodon is the signal sequence for mitochondrial import of glutamine tRNA in Tetrahymena Journal Article
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The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific Journal Article
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The coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation Journal Article
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The conserved RNA recognition motif 3 of U2 snRNA auxiliary factor (U2AF65) is essential in vivo but dispensable for activity in vitro Journal Article
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The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease Journal Article
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The functional significance of multimerization in ion channels Journal Article
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The gamma subunit of DNA polymerase III holoenzyme of Escherichia coli is produced by ribosomal frameshifting. Journal Article
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The gatekeeper residue controls autoactivation of ERK2 via a pathway of intramolecular connectivity Journal Article
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The genetic basis of modularity in the development and evolution of the vertebrate dentition Journal Article
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The iron exporter ferroportin 1 is essential for development of the mouse embryo, forebrain patterning and neural tube closure Journal Article
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The kinase suppressor of Ras (KSR) modulates growth factor and Ras signaling by uncoupling Elk-1 phosphorylation from MAP kinase activation Journal Article
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The large GTPase dynamin regulates actin comet formation and movement in living cells Journal Article
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The mammalian myosin heavy chain gene family Journal Article
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The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring Journal Article
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The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA Journal Article
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The role of Akt/GSK-3 beta signaling in familial hypertrophic cardiomyopathy Journal Article
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The sequence at specific positions in the early transcribed region sets the rate of transcript synthesis by RNA polymerase II in vitro Journal Article
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The spe-10 mutant has longer life and increased stress resistance Journal Article
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The structure of nucleosome assembly protein 1 Journal Article
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The tRNA specificity of Thermus thermophilus EF-Tu Journal Article
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Theoretical models of the influence of genomic architecture on the dynamics of speciation Journal Article
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Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain Journal Article
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Thermodynamic stability of wild-type and mutant p53 core domain Journal Article
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Tissue morphogenesis and vascular stability require the Frem2 protein, product of the mouse myelencephalic blebs gene Journal Article
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Toward the Rational Design of p53-Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant Journal Article
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Towards an understanding of the poliovirus replication complex: The solution structure of the soluble domain of the poliovirus 3A protein Journal Article
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Transcriptional profile of aging in C-elegans Journal Article
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Tuning the affinity of aminoacyl-tRNA to elongation factor Tu for optimal decoding. Journal Article
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Two major tertiary folding transitions of the Tetrahymena catalytic RNA. Journal Article
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Two pharmacologically distinct components of nicotinic receptor-mediated rubidium efflux in mouse brain require the beta 2 subunit Journal Article
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Two-step Ligand Binding in a (βα)8 Barrel Enzyme SUBSTRATE-BOUND STRUCTURES SHED NEW LIGHT ON THE CATALYTIC CYCLE OF HisA Journal Article
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UBQLN2 restrains the domesticated retrotransposon PEG10 to maintain neuronal health in ALS Journal Article
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UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C-elegans development Journal Article
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USB1 is a miRNA deadenylase that regulates hematopoietic development Journal Article
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Understanding Cardiomyopathy Phenotypes Based on the Functional Impact of Mutations in the Myosin Motor Journal Article
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Understanding the sequence specificity of tRNA binding to elongation factor Tu using tRNA mutagenesis. Journal Article
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Using a genetically targeted sensor to investigate the role of presenilin-1 in ER Ca2+ levels and dynamics Journal Article
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Variants of the yeast MAPK Mpk1 are fully functional independently of activation loop phosphorylation Journal Article
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WILD-TYPE BACTERIOPHAGE-T4 IS RESTRICTED BY THE LAMBDA-REX-GENES Journal Article
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Water-Restructuring Mutations Can Reverse the Thermodynamic Signature of Ligand Binding to Human Carbonic Anhydrase Journal Article
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Yeast telomerase is specialized for C/A-rich RNA templates Journal Article
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ZINC(II) AND THE SINGLE-STRANDED-DNA BINDING-PROTEIN OF BACTERIOPHAGE-T4 Journal Article
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Zebrafish furin mutants reveal intricacies in regulating Endothelin1 signaling in craniofacial patterning Journal Article
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Zic2 is required for enteric nervous system development and neurite outgrowth: a mouse model of enteric hyperplasia and dysplasia Journal Article
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Zinc transporters belonging to the Cation Diffusion Facilitator (CDF) family have complementary roles in transporting zinc out of the cytosol Journal Article
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dpa, a member of the MCM family, is required for mitotic DNA replication but not endoreplication in Drosophila. Journal Article
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lin-35/Rb and ubc-18, an E2 ubiquitin-conjugating enzyme, function redundantly to control pharyngeal morphogenesis in C-elegans Journal Article
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microRNAs play critical roles in the survival and recovery of Caenorhabditis elegans from starvation-induced L1 diapause Journal Article
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p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation Journal Article
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sem-4 promotes vulval cell-fate determination in Caenorhabditis elegans through regulation of lin-39 hox Journal Article
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tRNA residues evolved to promote translational accuracy. Journal Article
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tudor, a gene required for assembly of the germ plasm in Drosophila melanogaster. Journal Article
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β-catenin and its regulatory network Journal Article
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