The Eichel lab focuses on the mechanisms that enable neurons to establish and maintain their elaborate polarized architecture. We study both the neurodevelopmental pathways to establish key a neuronal structure called the axon initial segment and the membrane trafficking mechanisms that establish and maintain a polarized distribution of membrane proteins in the distinct neuronal domains of axons and dendrites. Elucidating these mechanisms promises insights into how polarity can be restored during the vast array of neurodevelopmental and neurodegenerative disorders that are associated with a loss of neuronal polarity.
MCDB 6000 - Introduction to Laboratory Methods
Primary Instructor
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Spring 2025 / Fall 2025
Introduces methodology and techniques used in biological research. Designed as a tutorial between a few students and one faculty member. Students are expected to read original research papers, discuss findings, and to plan and execute experiments in selected areas. May be repeated up to 15 total credit hours.
