MAPK and mTORC1 signaling converge to drive cyclin D1 protein production to enable cell cycle reentry in melanoma persister cells
Journal Article
Overview
publication date
- September 2, 2025
has subject area
- Biochemical Phenomena - MAP Kinase Signaling System
- Biochemical Phenomena - Signal Transduction
- Cell Cycle
- Cell Cycle Proteins - Cyclin D1
- Cell Line - Cell Line, Tumor
- Cell Physiological Phenomena - MAP Kinase Signaling System
- Cell Physiological Phenomena - Signal Transduction
- Drug Resistance, Neoplasm
- Humans
- Metabolic Networks and Pathways - MAP Kinase Signaling System
- Multiprotein Complexes - Mechanistic Target of Rapamycin Complex 1
- Neoplasms, Germ Cell and Embryonal - Melanoma
- Neoplasms, Nerve Tissue - Melanoma
- Nevi and Melanomas - Melanoma
- Peptides - Cyclin D1
- Peptides - Proto-Oncogene Proteins B-raf
- Protein-Serine-Threonine Kinases - Mechanistic Target of Rapamycin Complex 1
- Protein-Serine-Threonine Kinases - Proto-Oncogene Proteins B-raf
- Proteins - Cyclin D1
- Proteins - Mechanistic Target of Rapamycin Complex 1
- Proteins - Proto-Oncogene Proteins B-raf
- Proto-Oncogene Proteins - Cyclin D1
- Proto-Oncogene Proteins - Proto-Oncogene Proteins B-raf
- Tumor Cells, Cultured - Cell Line, Tumor
Date in CU Experts
- September 3, 2025 8:29 AM
Full Author List
- Nangia V; Ashraf H; Marikar N; Passanisi VJ; Ill CR; Spencer SL
author count
- 6
citation count
- 0
published in
- Science Signaling Journal
Other Profiles
International Standard Serial Number (ISSN)
- 1945-0877
Electronic International Standard Serial Number (EISSN)
- 1937-9145
Digital Object Identifier (DOI)
Additional Document Info
volume
- 18
issue
- 902
number
- ARTN eadw3231