Synergistic reduction in interfacial flexibility of TREM2R47H and ApoE4 may underlie AD pathology
Journal Article
Overview
publication date
- April 1, 2025
has subject area
- Apoproteins - Apolipoprotein E4
- Biochemical Phenomena - Molecular Dynamics Simulation
- Biochemical Phenomena - Protein Binding
- Brain Diseases - Alzheimer Disease
- Computer Simulation - Molecular Dynamics Simulation
- Humans
- Lipids - Apolipoprotein E4
- Membrane Proteins - Membrane Glycoproteins
- Metabolism - Protein Binding
- Models, Molecular - Molecular Dynamics Simulation
- Neurocognitive Disorders - Alzheimer Disease
- Protein Conformation
- Proteins - Apolipoprotein E4
- Proteins - Membrane Glycoproteins
- Receptors, Immunologic
- Tauopathies - Alzheimer Disease
has restriction
- hybrid
Date in CU Experts
- April 16, 2025 5:57 AM
Full Author List
- Lietzke EE; Saeb D; Aldrich EC; Bruce KD; Sprenger KG
author count
- 5
citation count
- 0
published in
- Alzheimer's and Dementia Journal
Other Profiles
International Standard Serial Number (ISSN)
- 1552-5260
Electronic International Standard Serial Number (EISSN)
- 1552-5279
Digital Object Identifier (DOI)
Additional Document Info
volume
- 21
issue
- 4
number
- ARTN e70120