Mutagenesis
PubMed MeSh Term
Overview
subject area of
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N-Ethyl-N-Nitrosourea (ENU) Mutagenesis Reveals an Intronic Residue Critical for Caenorhabditis elegans 3 Splice Site Function in Vivo Journal Article
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fzr-1 and lin-35/Rb function redundantly to control cell proliferation in C-elegans as revealed by a nonbiased synthetic screen Journal Article
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A Novel Saturation Mutagenesis Approach: Single Step Characterization of Regulatory Protein Binding Sites in RNA Using Phosphorothioates Journal Article
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A Transcriptional Enhancer from the Coding Region of ADAMTS5 Journal Article
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A Web Interface for Codon Compression Journal Article
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A gp330/megalin-related protein is required in the major epidermis of Caenorhabditis elegans for completion of molting Journal Article
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A novel mechanism underlies caspase-dependent conversion of the dicer ribonuclease into a deoxyribonuclease during apoptosis Journal Article
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A versatile platform strain for high-fidelity multiplex genome editing Journal Article
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AN INDEPENDENTLY FOLDING DOMAIN OF RNA TERTIARY STRUCTURE WITHIN THE TETRAHYMENA RIBOZYME Journal Article
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Activation of FAK and Src are receptor-proximal events required for netrin signaling Journal Article
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Activation of the erythropoietin receptor by the gp55-P viral envelope protein is determined by a single amino acid in its transmembrane domain Journal Article
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Acute effects of desmin mutations on cytoskeletal and cellular integrity in cardiac myocytes Journal Article
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An Automated Data-Driven Pipeline for Improving Heterologous Enzyme Expression Journal Article
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Analysis of a Critical Interaction within the Archaeal Box C/D Small Ribonucleoprotein Complex Journal Article
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CBASS Immunity Uses CARF-Related Effectors to Sense 3′-5′- and 2′-5′-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection Journal Article
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COMPARING MUTANTS, SELECTIVE BREEDING, AND TRANSGENICS IN THE DISSECTION OF AGING PROCESSES OF CAENORHABDITIS-ELEGANS Journal Article
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CRISPR/Cas9-mediated mutagenesis in the sea lamprey Petromyzon marinus: a powerful tool for understanding ancestral gene functions in vertebrates Journal Article
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Caenorhabditis elegans CED-9 protein is a bifunctional cell-death inhibitor Journal Article
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Caenorhabditis elegans SUR-5, a novel but conserved protein, negatively regulates LET-60 Ras activity during vulval induction Journal Article
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Codon Compression Algorithms for Saturation Mutagenesis Journal Article
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Conformational properties of oligonucleotides. Journal Article
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Conformational switches involved in orchestrating the successive steps of group I RNA splicing Journal Article
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Crystal Structure of BamB Bound to a Periplasmic Domain Fragment of BamA, the Central Component of the β-Barrel Assembly Machine Journal Article
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Crystals by design: A strategy for crystallization of a ribozyme derived from the Tetrahymena group I intron Journal Article
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Differential recognition of the polypyrimidine-tract by the general splicing factor U2AF65 and the splicing repressor sex-lethal Journal Article
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Directed evolution of excited state lifetime and brightness in FusionRed using a microfluidic sorter Journal Article
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Disruption of Gpr45 causes reduced hypothalamic POMC expression and obesity Journal Article
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Dynamic Management of Codon Compression for Saturation Mutagenesis Journal Article
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Efficient transposition of the piggyBac resource (PB) transposon in mammalian cells and mice Journal Article
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Elucidating sequence and solvent specific design targets to protect and stabilize enzymes for biocatalysis in ionic liquids Journal Article
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Expression of cardiac troponin T with COOH-terminal truncation accelerates cross-bridge interaction kinetics in mouse myocardium Journal Article
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GAAA TETRALOOP AND CONSERVED BULGE STABILIZE TERTIARY STRUCTURE OF A GROUP-I INTRON DOMAIN Journal Article
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Genetic suppression of cryoprotectant toxicity Journal Article
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High-Throughput Functional Genomics for Energy Production Journal Article
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INHIBITION OF THE CAENORHABDITIS-ELEGANS CELL-DEATH PROTEASE CED-3 BY A CED-3 CLEAVAGE SITE IN BACULOVIRUS P35 PROTEIN Journal Article
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INVITRO SELECTION OF RNAS THAT UNDERGO AUTOLYTIC CLEAVAGE WITH PB2+ Journal Article
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In vitro selection of RNAs that undergo autolytic cleavage with Pb2+. Journal Article
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In vitro selection of RNAs with increased tertiary structure stability Journal Article
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LDL-receptor-related protein 4 is crucial for formation of the neuromuscular junction Journal Article
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Lsm2 and Lsm3 bridge the interaction of the Lsm1-7 complex with Pat1 for decapping activation Journal Article
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MECHANISM OF DNA-REPLICATION FIDELITY FOR 3 MUTANTS OF DNA-POLYMERASE-I - KLENOW FRAGMENT KF(EXO+), KF(POLA5), AND KF(EXO-) Journal Article
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MEMO1 drives cranial endochondral ossification and palatogenesis Journal Article
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Melanoma subpopulations that rapidly escape MAPK pathway inhibition incur DNA damage and rely on stress signalling Journal Article
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Microfluidics-based selection of red-fluorescent proteins with decreased rates of photobleaching Journal Article
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Minor-groove recognition of double-stranded RNA by the double-stranded RNA-binding domain from the RNA-activated protein kinase PKR Journal Article
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Mitochondrial endonuclease G is important for apoptosis in C-elegans Journal Article
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Mutagenesis and comparative sequence analysis of a base triple joining the two domains of group I ribozymes Journal Article
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Mutagenesis of a stacking contact in the MS2 coat protein-RNA complex Journal Article
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Nonadditivity in the Recognition of Single-Stranded DNA by the Schizosaccharomyces pombe Protection of Telomeres 1 DNA-Binding Domain, Pot1-DBD Journal Article
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Nubp1 Is Required for Lung Branching Morphogenesis and Distal Progenitor Cell Survival in Mice Journal Article
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Optimization of multi-site nicking mutagenesis for generation of large, user-defined combinatorial libraries Journal Article
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Predicting Drug Resistance Using Deep Mutational Scanning Journal Article
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Preferential binding of the histone (H3-H4)2 tetramer by NAP1 is mediated by the amino-terminal histone tails Journal Article
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RNA SUBSTRATE BINDING-SITE IN THE CATALYTIC CORE OF THE TETRAHYMENA RIBOZYME Journal Article
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ROLE OF A RAF PROTOONCOGENE DURING CAENORHABDITIS-ELEGANS VULVAR DEVELOPMENT Journal Article
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Rapid Fine Conformational Epitope Mapping Using Comprehensive Mutagenesis and Deep Sequencing Journal Article
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Redox Regulation of SH2-Domain-Containing Protein Tyrosine Phosphatases by Two Backdoor Cysteines Journal Article
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Requirements for efficient ligand-gated co-transcriptional switching in designed variants of the B. subtilis pbuE adenine-responsive riboswitch in E. coli Journal Article
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STOPPING THE CLOCK Journal Article
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Saturation Mutagenesis Genome Engineering of Infective Phi X174 Bacteriophage via Unamplified Oligo Pools and Golden Gate Assembly Journal Article
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Standardizing cassette-based deep mutagenesis by Golden Gate assembly Journal Article
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Structural basis for endosomal targeting by the Bro1 domain Journal Article
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Structure of Est3 reveals a bimodal surface with differential roles in telomere replication Journal Article
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Structure, Function, and On-Off Switching of a Core Unit Contact between CheA Kinase and CheW Adaptor Protein in the Bacterial Chemosensory Array: A Disulfide Mapping and Mutagenesis Study Journal Article
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Substrate recognition by the AAA plus chaperone ClpB Journal Article
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Systematic mutagenesis of TFIIH subunit p52/Tfb2 identifies residues required for XPB/Ssl2 subunit function and genetic interactions with TFB6 Journal Article
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Targeted mutagenesis in human iPSCs using CRISPR genome-editing tools Journal Article
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Thailandenes, Cryptic Polyene Natural Products Isolated from Burkholderia thailandensis Using Phenotype-Guided Transposon Mutagenesis Journal Article
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The Histone Methyltransferase Ash1l is Required for Epidermal Homeostasis in Mice Journal Article
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The base substitution and frameshift fidelity of Escherichia coli DNA polymerase III holoenzyme in vitro. Journal Article
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Three ever shorter telomere (EST) genes are dispensable for in vitro yeast telomerase activity Journal Article
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Using genomewide mutagenesis screens to identify the genes required for neural tube closure in the mouse Journal Article
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Yin Yang 1 is increased in human heart failure and represses the activity of the human α-myosin heavy chain promoter Journal Article
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