Caenorhabditis elegans Proteins PubMed MeSh Term

Overview

subject area of

• 25 years after age-1: Genes, interventions and the revolution in aging research  Journal Article
• C-elegans Rb, NuRD, and Ras regulate lin-39-mediated cell fusion during vulval fate specification  Journal Article
• C-elegans mitochondrial factor WAH-1 promotes phosphatidylserine externalization in apoptotic cells through phospholipid scramblase SCRM-1  Journal Article
• Caenorhabditis elegans drp-1 and fis-2 regulate distinct cell-death execution pathways downstream of ced-3 and independent of ced-9  Journal Article
• Caenorhabditis elegans caspase homolog CSP-2 inhibits CED-3 autoactivation and apoptosis in germ cells  Journal Article
• Caenorhabditis elegans transthyretin-like protein TTR-52 mediates recognition of apoptotic cells by the CED-1 phagocyte receptor  Journal Article
• Cis regulatory requirements for vulval cell-specific expression of the Caenorhabditis elegans fibroblast growth factor gene egl-17  Journal Article
• daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans  Journal Article
• daf-16 protects the nematode Caenorhabditis elegans during food deprivation  Journal Article
• fzr-1 and lin-35/Rb function redundantly to control cell proliferation in C-elegans as revealed by a nonbiased synthetic screen  Journal Article
• unc-83 encodes a novel component of the nuclear envelope and is essential for proper nuclear migration  Journal Article
• A Lipid-TORC1 Pathway Promotes Neuronal Development and Foraging Behavior under Both Fed and Fasted Conditions in C. elegans  Journal Article
• A PP2A regulatory subunit positively regulates Ras-mediated signaling during Caenorhabditis elegans vulval induction  Journal Article
• A Ras-mediated signal transduction pathway is involved in the control of sex myoblast migration in Caenorhabditis elegans  Journal Article
• A class of benzenoid chemicals suppresses apoptosis in C. elegans  Journal Article
• A cuticle collagen encoded by the lon-3 gene may be a target of TGF-β signaling in determining Caenorhabditis elegans body shape  Journal Article
• A gain-of-function allele of cbp-1, the Caenorhabditis elegans ortholog of the mammalian CBP/p300 gene, causes an increase in histone acetyltransferase activity and antagonism of activated Ras  Journal Article
• A lysine-rich motif in the phosphatidylserine receptor PSR-1 mediates recognition and removal of apoptotic cells  Journal Article
• A new marker for mosaic analysis in Caenorhabditis elegans indicates a fusion between hyp6 and hyp7, two major components of the hypodermis  Journal Article
• A novel mechanism underlies caspase-dependent conversion of the dicer ribonuclease into a deoxyribonuclease during apoptosis  Journal Article
• A novel sphingolipid-TORC1 pathway critically promotes postembryonic development in Caenorhabditis elegans  Journal Article
• A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans  Journal Article
• AIP-1 ameliorates beta-amyloid peptide toxicity in a Caenorhabditis elegans Alzheimer's disease model  Journal Article
• ANALYSIS OF DOMINANT-NEGATIVE MUTATIONS OF THE CAENORHABDITIS-ELEGANS LET-60 RAS GENE  Journal Article
• ANChors away: an actin based mechanism of nuclear positioning  Journal Article
• Activation of SKN-1 by novel kinases in Caenorhabditis elegans  Journal Article
• Allele-Specific Suppressors of lin-1(R175Opal) Identify Functions of MOC-3 and DPH-3 in tRNA Modification Complexes in Caenorhabditis elegans  Journal Article
• An elt-3/elt-5/elt-6 GATA transcription circuit guides aging in C-elegans  Journal Article
• Analysis of programmed cell death in the nematode Caenorhabditis elegans  Journal Article
• Bcl-2 Proteins EGL-1 and CED-9 Do Not Regulate Mitochondrial Fission or Fusion in Caenorhabditis elegans  Journal Article
• C-ELEGANS LIN-45 RAF GENE PARTICIPATES IN LET-60 RAS-STIMULATED VULVAR DIFFERENTIATION  Journal Article
• CED-1, CED-7, and TTR-52 Regulate Surface Phosphatidylserine Expression on Apoptotic and Phagocytic Cells  Journal Article
• CED-3 caspase acts with miRNAs to regulate non-apoptotic gene expression dynamics for robust development in C. elegans  Journal Article
• COG-2, a Sox domain protein necessary for establishing a functional vulval-uterine connection in Caenorhabditis elegans  Journal Article
• COOPERATIVE INTERACTIONS BETWEEN THE CAENORHABDITIS-ELEGANS HOMEOPROTEINS UNC-86 AND MEC-3  Journal Article
• CRN-1, a Caenorhabditis elegans FEN-1 homologue, cooperates with CPS-6/EndoG to promote apoptotic DNA degradation  Journal Article
• Caenorhabditis elegans 2007: The premier model for the study of aging  Journal Article
• Caenorhabditis elegans CED-9 protein is a bifunctional cell-death inhibitor  Journal Article
• Caenorhabditis elegans EVL-14/PDS-5 and SCC-3 are essential for sister chromatid cohesion in meiosis and mitosis  Journal Article
• Caenorhabditis elegans SUR-5, a novel but conserved protein, negatively regulates LET-60 Ras activity during vulval induction  Journal Article
• Casein Kinase 1δ Stabilizes Mature Axons by Inhibiting Transcription Termination of Ankyrin  Journal Article
• Caspase-Dependent Conversion of Dicer Ribonuclease into a Death-Promoting Deoxyribonuclease  Journal Article
• Caspase-activated phosphoinositide binding by CNT-1 promotes apoptosis by inhibiting the AKT pathway  Journal Article
• Caspase-mediated activation of Caenorhabditis elegans CED-8 promotes apoptosis and phosphatidylserine externalization  Journal Article
• Cell Death by Glutamine Repeats?  Journal Article
• Cell corpse engulfment mediated by C-elegans phosphatidylserine receptor through CED-5 and CED-12  Journal Article
• Cell death specification in C-elegans  Journal Article
• Coenzyme Q supports distinct developmental processes in Caenorhabditis elegans  Journal Article
• Compensatory regulation among ER chaperones in C. elegans  Journal Article
• Control of sex-specific apoptosis in C-elegans by the BarH homeodomain protein CEH-30 and the transcriptional repressor UNC-37/Groucho  Journal Article
• Coupled Caspase and N-End Rule Ligase Activities Allow Recognition and Degradation of Pluripotency Factor LIN-28 during Non-Apoptotic Development  Journal Article
• Cryoprotectant toxicity in Caenorhabditis elegans  Journal Article
• Crystal Structure of CRN-4: Implications for Domain Function in Apoptotic DNA Degradation  Journal Article
• Cysteine protease cathepsin B mediates radiation-induced bystander effects  Journal Article
• Cytoplasmic dynein light intermediate chain is required for discrete aspects of mitosis in Caenorhabditis elegans  Journal Article
• DLK-1, SEK-3 and PMK-3 Are Required for the Life Extension Induced by Mitochondrial Bioenergetic Disruption in C. elegans  Journal Article
• Demonstration of the in vivo interaction of key cell death regulators by structure-based design of second-site suppressors  Journal Article
• Developmental Defects of Caenorhabditis elegans Lacking Branched-chain α-Ketoacid Dehydrogenase Are Mainly Caused by Monomethyl Branched-chain Fatty Acid Deficiency  Journal Article
• Dicing up chromosomes The unexpected role of dicer in apoptosis  Journal Article
• EFF-1-mediated regenerative axonal fusion requires components of the apoptotic pathway  Journal Article
• Elimination of paternal mitochondria through the lysosomal degradation pathway in C. elegans  Journal Article
• Evolutionary rate in the protein interaction network  Journal Article
• Expression of a Single-Copy hsp-16.2 Reporter Predicts Life span  Journal Article
• Expression of the small heat-shock protein Hsp-16-2 in Caenorhabditis elegans is suppressed by Ginkgo biloba extract EGb 761  Journal Article
• Extending life-span in C-elegans  Journal Article
• Fatty Acids Regulate Germline Sex Determination through ACS-4-Dependent Myristoylation  Journal Article
• Fatty acids impact sarcomere integrity through myristoylation and ER homeostasis  Journal Article
• Functional genomic analysis of apoptotic DNA degradation in C-elegans  Journal Article
• Fusogenic activity of EFF-1 is regulated via dynamic localization in fusing somatic cells of C-elegans  Journal Article
• Genes involved in pre-mRNA 3′-end formation and transcription termination revealed by a lin-15 operon Muv suppressor screen  Journal Article
• Genes, Phenes, and Dreams of Immortality: The 2003 Kleemeier Award Lecture  Journal Article
• Genetic Mechanisms of Coffee Extract Protection in a Caenorhabditis elegans Model of β-Amyloid Peptide Toxicity  Journal Article
• Genetic redundancy masks diverse functions of the tumor suppressor gene PTEN during C-elegans development  Journal Article
• Genetics of RAS signaling in C-elegans  Journal Article
• Gerontogenes mediate health and longevity in nematodes through increasing resistance to environmental toxins and stressors  Journal Article
• Heat shock in C. elegans induces downstream of gene transcription and accumulation of double-stranded RNA  Journal Article
• Heat shock protein accumulation is upregulated in a long-lived mutant of Caenorhabditis elegans  Journal Article
• Hedgehog signalling in the mouse requires intraflagellar transport proteins  Journal Article
• Hepatitis B virus X protein targets the Bcl-2 protein CED-9 to induce intracellular Ca²⁺ increase and cell death in Caenorhabditis elegans  Journal Article
• Hormesis and aging in Caenorhabditis elegans  Journal Article
• Human ACAP2 is a homolog of C. elegans CNT-1 that promotes apoptosis in cancer cells  Journal Article
• INHIBITION OF THE CAENORHABDITIS-ELEGANS CELL-DEATH PROTEASE CED-3 BY A CED-3 CLEAVAGE SITE IN BACULOVIRUS P35 PROTEIN  Journal Article
• Identification of CED-3 substrates by a yeast-based screening method  Journal Article
• In vivo induction of membrane damage by beta-amyloid peptide oligomers  Journal Article
• Inferring temporal organization of postembryonic development from high-content behavioral tracking  Journal Article
• Infertility and recurrent miscarriage with complex II deficiency-dependent mitochondrial oxidative stress in animal models  Journal Article
• Inhibition of CED-3 zymogen activation and apoptosis in Caenorhabditis elegans by caspase homolog CSP-3  Journal Article
• Insulin-like Signaling Determines Survival during Stress via Posttranscriptional Mechanisms in C. elegans  Journal Article
• Interaction of intracellular β amyloid peptide with chaperone proteins  Journal Article
• Intestinal apical polarity mediates regulation of TORC1 by glucosylceramide in C. elegans  Journal Article
• Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization  Journal Article
• Lamin-dependent localization of UNC-84, a protein required for nuclear migration in Caenorhabditis elegans  Journal Article
• Life extension and stress resistance in Caenorhabditis elegans modulated by the tkr-1 gene  Journal Article
• Life-span extension by dietary restriction is mediated by NLP-7 signaling and coelomocyte endocytosis in C. elegans  Journal Article
• Lin-35/Rb cooperates with the SWI/SNF complex to control Caenorhabditis elegans larval development  Journal Article
• Localization of RNAPII and 3 ' end formation factor CstF subunits on C. elegans genes and operons  Journal Article
• Long-lived mitochondrial (Mit) mutants of Caenorhabditis elegans utilize a novel metabolism  Journal Article
• Longevity genes in the nematode Caenorhabditis elegans also mediate increased resistance to stress and prevent disease  Journal Article
• Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation  Journal Article
• Loss of miR-83 extends lifespan and affects target gene expression in an age-dependent manner in Caenorhabditis elegans  Journal Article
• Mechanisms of AIF-mediated apoptotic DNA degradation in Caenorhabditis elegans  Journal Article
• Methods for Studying Programmed Cell Death in C. elegans  Journal Article
• Microbial Siderophore Enterobactin Promotes Mitochondrial Iron Uptake and Development of the Host via Interaction with ATP Synthase  Journal Article
• Mitochondrial Cell Death Pathways in Caenorhabiditis elegans  Journal Article
• Mitochondrial Dysfunction in C. elegans Activates Mitochondrial Relocalization and Nuclear Hormone Receptor-Dependent Detoxification Genes  Journal Article
• Mitochondrial endonuclease G is important for apoptosis in C-elegans  Journal Article
• Mitochondrial endonuclease G mediates breakdown of paternal mitochondria upon fertilization  Journal Article
• Moderate embryonic delay of paternal mitochondrial elimination impairs mating and cognition and alters behaviors of adult animals  Journal Article
• Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR-1 kinase and PP2A phosphatase  Journal Article
• Monomethyl branched-chain fatty acids play an essential role in Caenorhabditis elegans development  Journal Article
• Mortality shifts in Caenorhabditis elegans: remembrance of conditions past  Journal Article
• Multiple mechanisms are involved in regulating the expression of the developmental timing regulator lin-28 in Caenorhabditis elegans  Journal Article
• Muscle cell migrations of C. elegans are mediated by the alpha-integrin INA-1, Eph receptor VAB-1, and a novel peptidase homologue MNP-1  Journal Article
• Neurotoxic effects of TDP-43 overexpression in C-elegans  Journal Article
• Non-Canonical Caspase Activity Antagonizes p38 MAPK Stress-Priming Function to Support Development  Journal Article
• Nuclear Migration: Rock and Roll Facilitated by Dynein and Kinesin  Journal Article
• Nucleotide levels regulate germline proliferation through modulating GLP-1/Notch signaling in C. elegans  Journal Article
• Oligonucleotide-based targeted gene editing in C. elegans via the CRISPR/Cas9 system  Journal Article
• Oxidative Stress Impairs Cell Death by Repressing the Nuclease Activity of Mitochondrial Endonuclease G  Journal Article
• Oxidative stress and longevity in Caenorhabditis elegans as mediated by SKN-1  Journal Article
• P-Type ATPase TAT-2 Negatively Regulates Monomethyl Branched-Chain Fatty Acid Mediated Function in Post-Embryonic Growth and Development in C. elegans  Journal Article
• Pattern Formation in the Longevity-Related Expression of Heat Shock Protein-16.2 in Caenorhabditis elegans  Journal Article
• Peroxisome Protein Transportation Affects Metabolism of Branched-Chain Fatty Acids That Critically Impact Growth and Development of C. elegans  Journal Article
• Post-embryonic expression pattern of C-elegans let-60 ras reporter constructs  Journal Article
• Predicting longevity in C-elegans: Fertility, mobility and gene expression  Journal Article
• Programmed Cell Death During Caenorhabditis elegans Development  Journal Article
• Proteasomal dysfunction activates the transcription factor SKN-1 and produces a selective oxidative-stress response in Caenorhabditis elegans  Journal Article
• Protective Role of DNJ-27/ERdj5 in Caenorhabditis elegans Models of Human Neurodegenerative Diseases  Journal Article
• Proteomic identification of proteins specifically oxidized in Caenorhabditis elegans expressing human Aβ(1-42):: Implications for Alzheimer's disease  Journal Article
• Quantifying Phenotypic Variation in Isogenic Caenorhabditis elegans Expressing Phsp-16.2::gfp by Clustering 2D Expression Patterns  Journal Article
• REGULATION OF THE MEC-3-GENE BY THE C-ELEGANS HOMEOPROTEINS UNC-86 AND MEC-3  Journal Article
• RNA Binding Protein Vigilin Collaborates with miRNAs To Regulate Gene Expression for Caenorhabditis elegans Larval Development  Journal Article
• RNA aptamers targeting the cell death inhibitor CED-9 induce cell killing in Caenorhabditis elegans  Journal Article
• Ras is required for a limited number of cell fates and not for general proliferation in Caenorhabditis elegans  Journal Article
• Ras proteins in developmental pattern formation in Caenorhabditis elegans and Drosophila.  Journal Article
• Re-evaluating the role of ELT-3 in a GATA transcription factor circuit proposed to guide aging in C. elegans Response  Journal Article
• Reconciliation of daf-2 suppression by elt-3 in Caenorhabditis elegans from Tonsaker et al. (2012) and Kim et al. (2012)  Journal Article
• Reduced expression of the Caenorhabditis elegans p53 ortholog cep-1 results in increased longevity  Journal Article
• Regulation of CED-3 caspase localization and activation by C-elegans nuclear-membrane protein NPP-14  Journal Article
• Repression of Germline RNAi Pathways in Somatic Cells by Retinoblastoma Pathway Chromatin Complexes  Journal Article
• Role of C-elegans TAT-1 protein in maintaining plasma membrane phosphatidylserine asymmetry  Journal Article
• Role of ANC-1 in tethering nuclei to the actin cytoskeleton.  Journal Article
• Role of C-elegans lin-40 MTA in vulval fate specification and morphogenesis  Journal Article
• Roles of chromatin factors in C. elegans development.  Journal Article
• SKR-1, a homolog of Skp1 and a member of the SCF^SEL-10 complex, regulates sex-determination and LIN-12/Notch signaling in C. elegans  Journal Article
• SUPPRESSION OF ACTIVATED LET-60 RAS PROTEIN DEFINES A ROLE OF CAENORHABDITIS-ELEGANS SUR-1 MAP KINASE IN VULVAR DIFFERENTIATION  Journal Article
• SUR-2, A NOVEL GENE, FUNCTIONS LATE IN THE LET-60 RAS-MEDIATED SIGNALING PATHWAY DURING CAENORHABDITIS-ELEGANS VULVAR INDUCTION  Journal Article
• SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C-elegans  Journal Article
• Single Cell Quantification of Reporter Gene Expression in Live Adult Caenorhabditis elegans Reveals Reproducible Cell-Specific Expression Patterns and Underlying Biological Variation  Journal Article
• Somatic sex determination in Caenorhabditis elegans is modulated by SUP-26 repression of tra-2 translation  Journal Article
• Starvation-Induced Stress Response Is Critically Impacted by Ceramide Levels in Caenorhabditis elegans  Journal Article
• Structural Insights into Apoptotic DNA Degradation by CED-3 Protease Suppressor-6 (CPS-6) from Caenorhabditis elegans  Journal Article
• Structural analysis of the ZEN-4/CeMKLP1 motor domain and its interaction with microtubules  Journal Article
• Structural, biochemical, and functional analyses of CED-9 recognition by the proapoptotic proteins EGL-1 and CED-4  Journal Article
• Structure and function analysis of the C-elegans aminophospholipid translocase TAT-1  Journal Article
• Structure of the CED-4-CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans  Journal Article
• Studying polyglutamine aggregation in Caenorhabditis elegans using an analytical ultracentrifuge equipped with fluorescence detection  Journal Article
• Suppression of in vivo β-amyloid peptide toxicity by overexpression of the HSP-16.2 small chaperone protein  Journal Article
• SynMuv genes redundantly inhibit lin-31EGF expression to prevent inappropriate vulval induction in C-elegans  Journal Article
• Syntaxin N-terminal peptide motif is an initiation factor for the assembly of the SNARE-Sec1/Munc18 membrane fusion complex  Journal Article
• Systematic Analysis of Tissue-Restricted miRISCs Reveals a Broad Role for MicroRNAs in Suppressing Basal Activity of the C. elegans Pathogen Response  Journal Article
• Systematic analysis of dynamic miRNA-target interactions during C. elegans development  Journal Article
• Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2  Journal Article
• TDP-1, the Caenorhabditis elegans ortholog of TDP-43, limits the accumulation of double-stranded RNA  Journal Article
• Tag team: Roles of miRNAs and Proteolytic Regulators in Ensuring Robust Gene Expression Dynamics  Journal Article
• The C-elegans evl-20 gene is a homolog of the small GTPase ARL2 and regulates cytoskeleton dynamics during cytokinesis and morphogenesis  Journal Article
• The Caenorhabditis elegans aristaless orthologue, alr-1, is required for maintaining the functional and structural integrity of the amphid sensory organs  Journal Article
• The Caenorhabditis elegans ect-2 RhoGEF gene regulates cytokinesis and migration of epidermal P cells  Journal Article
• The Caenorhabditis elegans EGL-26 protein mediates vulval cell morphogenesis  Journal Article
• The Caenorhabditis elegans Ortholog of TDP-43 Regulates the Chromatin Localization of the Heterochromatin Protein 1 Homolog HPL-2  Journal Article
• The Caenorhabditis elegans nuclear receptor gene nhr-25 regulates epidermal cell development  Journal Article
• The Apoptotic Engulfment Machinery Regulates Axonal Degeneration in C-elegans Neurons  Journal Article
• The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease  Journal Article
• The GATA Factor elt-1 Regulates C. elegans Developmental Timing by Promoting Expression of the let-7 Family MicroRNAs  Journal Article
• The OLD-1 positive regulator of longevity and stress resistance is under DAF-16 regulation in Caenorhabditis elegans  Journal Article
• The Tumor Suppressor Rb Critically Regulates Starvation-Induced Stress Response in C. elegans  Journal Article
• The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegans  Journal Article
• The fatty acid synthase fasn-1 acts upstream of WNK and Ste20/GCK-VI kinases to modulate antimicrobial peptide expression in C. elegans epidermis  Journal Article
• The genetic core of the universal ancestor  Journal Article
• The leucine-rich repeat protein SUR-8 enhances MAP kinase activation and forms a complex with Ras and Raf  Journal Article
• The nongenotoxic carcinogens naphthalene and para-dichlorobenzene suppress apoptosis in Caenorhabditis elegans  Journal Article
• Time to move the fat  Journal Article
• Twists and turns-How we stepped into and had fun in the "boring" lipid field  Journal Article
• UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C-elegans development  Journal Article
• Visualizing hidden heterogeneity in isogenic populations of C-elegans  Journal Article
• Visualizing the metazoan proliferation-quiescence decision in vivo  Journal Article
• lin-35/Rb and ubc-18, an E2 ubiquitin-conjugating enzyme, function redundantly to control pharyngeal morphogenesis in C-elegans  Journal Article
• p53/CEP-1 increases or decreases lifespan, depending on level of mitochondrial bioenergetic stress  Journal Article
• sem-4 promotes vulval cell-fate determination in Caenorhabditis elegans through regulation of lin-39 hox  Journal Article

broader concept

• Helminth Proteins  PubMed MeSh Term